node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spro_0166 | wecD | Spro_0166 | Spro_0167 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.849 |
Spro_0166 | wecE | Spro_0166 | Spro_0168 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | TDP-4-keto-6-deoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. | 0.930 |
Spro_0166 | wecF | Spro_0166 | Spro_0170 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.802 |
Spro_0166 | wecG | Spro_0166 | Spro_0172 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | Glycosyl transferase, WecB/TagA/CpsF family; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. | 0.821 |
Spro_0166 | wzxE | Spro_0166 | Spro_0169 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.924 |
Spro_0166 | wzyE | Spro_0166 | Spro_0171 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | WzyE family protein; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.806 |
Spro_0166 | wzzE | Spro_0166 | Spro_0162 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | Lipopolysaccharide biosynthesis protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. | 0.525 |
Spro_1092 | Spro_2806 | Spro_1092 | Spro_2806 | PFAM: Uncharacterized lipoprotein; KEGG: ypi:YpsIP31758_3095 putative lipoprotein. | PFAM: protein of unknown function UPF0181; KEGG: ypi:YpsIP31758_2352 hypothetical protein; Belongs to the UPF0181 family. | 0.718 |
Spro_1092 | Spro_4809 | Spro_1092 | Spro_4809 | PFAM: Uncharacterized lipoprotein; KEGG: ypi:YpsIP31758_3095 putative lipoprotein. | KEGG: stm:STM4060 periplasmic repressor of cpx regulon by interaction with CpxA, rescue from transitory stresses. | 0.771 |
Spro_1092 | wecD | Spro_1092 | Spro_0167 | PFAM: Uncharacterized lipoprotein; KEGG: ypi:YpsIP31758_3095 putative lipoprotein. | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.771 |
Spro_1092 | wecF | Spro_1092 | Spro_0170 | PFAM: Uncharacterized lipoprotein; KEGG: ypi:YpsIP31758_3095 putative lipoprotein. | 4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.774 |
Spro_1092 | wzxE | Spro_1092 | Spro_0169 | PFAM: Uncharacterized lipoprotein; KEGG: ypi:YpsIP31758_3095 putative lipoprotein. | Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.751 |
Spro_1092 | wzyE | Spro_1092 | Spro_0171 | PFAM: Uncharacterized lipoprotein; KEGG: ypi:YpsIP31758_3095 putative lipoprotein. | WzyE family protein; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.774 |
Spro_1092 | wzzE | Spro_1092 | Spro_0162 | PFAM: Uncharacterized lipoprotein; KEGG: ypi:YpsIP31758_3095 putative lipoprotein. | Lipopolysaccharide biosynthesis protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. | 0.690 |
Spro_2806 | Spro_1092 | Spro_2806 | Spro_1092 | PFAM: protein of unknown function UPF0181; KEGG: ypi:YpsIP31758_2352 hypothetical protein; Belongs to the UPF0181 family. | PFAM: Uncharacterized lipoprotein; KEGG: ypi:YpsIP31758_3095 putative lipoprotein. | 0.718 |
Spro_2806 | Spro_4809 | Spro_2806 | Spro_4809 | PFAM: protein of unknown function UPF0181; KEGG: ypi:YpsIP31758_2352 hypothetical protein; Belongs to the UPF0181 family. | KEGG: stm:STM4060 periplasmic repressor of cpx regulon by interaction with CpxA, rescue from transitory stresses. | 0.619 |
Spro_2806 | wecD | Spro_2806 | Spro_0167 | PFAM: protein of unknown function UPF0181; KEGG: ypi:YpsIP31758_2352 hypothetical protein; Belongs to the UPF0181 family. | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.758 |
Spro_2806 | wecF | Spro_2806 | Spro_0170 | PFAM: protein of unknown function UPF0181; KEGG: ypi:YpsIP31758_2352 hypothetical protein; Belongs to the UPF0181 family. | 4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.765 |
Spro_2806 | wzxE | Spro_2806 | Spro_0169 | PFAM: protein of unknown function UPF0181; KEGG: ypi:YpsIP31758_2352 hypothetical protein; Belongs to the UPF0181 family. | Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.689 |
Spro_2806 | wzyE | Spro_2806 | Spro_0171 | PFAM: protein of unknown function UPF0181; KEGG: ypi:YpsIP31758_2352 hypothetical protein; Belongs to the UPF0181 family. | WzyE family protein; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.753 |