node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spro_0683 | Spro_4344 | Spro_0683 | Spro_4344 | Aspartate kinase; KEGG: yps:YPTB0602 bifunctional ThrA; aspartokinase I and homoserine dehydrogenase I (C-terminal); TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | 0.763 |
Spro_0683 | Spro_4785 | Spro_0683 | Spro_4785 | Aspartate kinase; KEGG: yps:YPTB0602 bifunctional ThrA; aspartokinase I and homoserine dehydrogenase I (C-terminal); TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | Aspartate kinase; KEGG: yen:YE0112 bifunctional aspartokinase/homoserine dehydrogenase II; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.991 |
Spro_0683 | argA | Spro_0683 | Spro_3812 | Aspartate kinase; KEGG: yps:YPTB0602 bifunctional ThrA; aspartokinase I and homoserine dehydrogenase I (C-terminal); TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: yen:YE3308 amino-acid acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. | 0.523 |
Spro_0683 | argB | Spro_0683 | Spro_4780 | Aspartate kinase; KEGG: yps:YPTB0602 bifunctional ThrA; aspartokinase I and homoserine dehydrogenase I (C-terminal); TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. | 0.639 |
Spro_0683 | argG | Spro_0683 | Spro_4779 | Aspartate kinase; KEGG: yps:YPTB0602 bifunctional ThrA; aspartokinase I and homoserine dehydrogenase I (C-terminal); TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | PFAM: argininosuccinate synthase; KEGG: plu:plu4742 argininosuccinate synthase (citrulline-aspartate ligase); Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.917 |
Spro_0683 | proA | Spro_0683 | Spro_0968 | Aspartate kinase; KEGG: yps:YPTB0602 bifunctional ThrA; aspartokinase I and homoserine dehydrogenase I (C-terminal); TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.531 |
Spro_0683 | proB | Spro_0683 | Spro_0967 | Aspartate kinase; KEGG: yps:YPTB0602 bifunctional ThrA; aspartokinase I and homoserine dehydrogenase I (C-terminal); TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.546 |
Spro_0683 | proC | Spro_0683 | Spro_4031 | Aspartate kinase; KEGG: yps:YPTB0602 bifunctional ThrA; aspartokinase I and homoserine dehydrogenase I (C-terminal); TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.493 |
Spro_2931 | Spro_4344 | Spro_2931 | Spro_4344 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | 0.943 |
Spro_2931 | argG | Spro_2931 | Spro_4779 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | PFAM: argininosuccinate synthase; KEGG: plu:plu4742 argininosuccinate synthase (citrulline-aspartate ligase); Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.401 |
Spro_2931 | proA | Spro_2931 | Spro_0968 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.949 |
Spro_2931 | proB | Spro_2931 | Spro_0967 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.943 |
Spro_2931 | proC | Spro_2931 | Spro_4031 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.955 |
Spro_4344 | Spro_0683 | Spro_4344 | Spro_0683 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | Aspartate kinase; KEGG: yps:YPTB0602 bifunctional ThrA; aspartokinase I and homoserine dehydrogenase I (C-terminal); TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | 0.763 |
Spro_4344 | Spro_2931 | Spro_4344 | Spro_2931 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.943 |
Spro_4344 | Spro_4785 | Spro_4344 | Spro_4785 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | Aspartate kinase; KEGG: yen:YE0112 bifunctional aspartokinase/homoserine dehydrogenase II; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.763 |
Spro_4344 | argA | Spro_4344 | Spro_3812 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: yen:YE3308 amino-acid acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. | 0.587 |
Spro_4344 | argB | Spro_4344 | Spro_4780 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. | 0.648 |
Spro_4344 | argG | Spro_4344 | Spro_4779 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | PFAM: argininosuccinate synthase; KEGG: plu:plu4742 argininosuccinate synthase (citrulline-aspartate ligase); Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.509 |
Spro_4344 | proA | Spro_4344 | Spro_0968 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.899 |