node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spro_0219 | Spro_1935 | Spro_0219 | Spro_1935 | PFAM: protein of unknown function DUF1145; KEGG: yen:YE0223 hypothetical protein. | PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein. | 0.771 |
Spro_0219 | Spro_2127 | Spro_0219 | Spro_2127 | PFAM: protein of unknown function DUF1145; KEGG: yen:YE0223 hypothetical protein. | KEGG: yen:YE1891 putative yfeABCD locus regulator. | 0.771 |
Spro_0219 | Spro_4039 | Spro_0219 | Spro_4039 | PFAM: protein of unknown function DUF1145; KEGG: yen:YE0223 hypothetical protein. | KEGG: yen:YE3439 hypothetical protein. | 0.773 |
Spro_0219 | lpoA | Spro_0219 | Spro_4336 | PFAM: protein of unknown function DUF1145; KEGG: yen:YE0223 hypothetical protein. | LppC family lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | 0.757 |
Spro_0219 | matP | Spro_0219 | Spro_1753 | PFAM: protein of unknown function DUF1145; KEGG: yen:YE0223 hypothetical protein. | Protein of unknown function DUF1047; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. | 0.770 |
Spro_0219 | mukB | Spro_0219 | Spro_1725 | PFAM: protein of unknown function DUF1145; KEGG: yen:YE0223 hypothetical protein. | Chromosome segregation and condensation protein MukB domain protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. | 0.519 |
Spro_0219 | mukE | Spro_0219 | Spro_1724 | PFAM: protein of unknown function DUF1145; KEGG: yen:YE0223 hypothetical protein. | Chromosome segregation and condensation protein MukE; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. | 0.570 |
Spro_0219 | mukF | Spro_0219 | Spro_1723 | PFAM: protein of unknown function DUF1145; KEGG: yen:YE0223 hypothetical protein. | Chromosome segregation and condensation protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. | 0.585 |
Spro_0219 | trpR | Spro_0219 | Spro_0676 | PFAM: protein of unknown function DUF1145; KEGG: yen:YE0223 hypothetical protein. | Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | 0.782 |
Spro_1935 | Spro_0219 | Spro_1935 | Spro_0219 | PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein. | PFAM: protein of unknown function DUF1145; KEGG: yen:YE0223 hypothetical protein. | 0.771 |
Spro_1935 | Spro_2127 | Spro_1935 | Spro_2127 | PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein. | KEGG: yen:YE1891 putative yfeABCD locus regulator. | 0.771 |
Spro_1935 | Spro_4039 | Spro_1935 | Spro_4039 | PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein. | KEGG: yen:YE3439 hypothetical protein. | 0.773 |
Spro_1935 | lpoA | Spro_1935 | Spro_4336 | PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein. | LppC family lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | 0.755 |
Spro_1935 | matP | Spro_1935 | Spro_1753 | PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein. | Protein of unknown function DUF1047; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. | 0.763 |
Spro_1935 | mukE | Spro_1935 | Spro_1724 | PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein. | Chromosome segregation and condensation protein MukE; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. | 0.459 |
Spro_1935 | mukF | Spro_1935 | Spro_1723 | PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein. | Chromosome segregation and condensation protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. | 0.524 |
Spro_1935 | trpR | Spro_1935 | Spro_0676 | PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein. | Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | 0.759 |
Spro_2127 | Spro_0219 | Spro_2127 | Spro_0219 | KEGG: yen:YE1891 putative yfeABCD locus regulator. | PFAM: protein of unknown function DUF1145; KEGG: yen:YE0223 hypothetical protein. | 0.771 |
Spro_2127 | Spro_1935 | Spro_2127 | Spro_1935 | KEGG: yen:YE1891 putative yfeABCD locus regulator. | PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein. | 0.771 |
Spro_2127 | Spro_4039 | Spro_2127 | Spro_4039 | KEGG: yen:YE1891 putative yfeABCD locus regulator. | KEGG: yen:YE3439 hypothetical protein. | 0.774 |