STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folE2Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate. (309 aa)    
Predicted Functional Partners:
Spro_0809
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: ypi:YpsIP31758_3312 putative 6-pyruvoyl tetrahydrobiopterin synthase.
    
 0.927
Spro_3321
PFAM: dihydroneopterin aldolase; KEGG: sdy:SDY_2500 D-erythro-7,8-dihydroneopterin tri P epimerase.
 
  
 0.922
folE
PFAM: GTP cyclohydrolase I; KEGG: eca:ECA2711 GTP cyclohydrolase I.
     
 0.920
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
     
 0.904
Spro_2626
PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: csa:Csal_0192 cobalamin synthesis protein, P47K.
 
  
 0.903
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
     
  0.900
Spro_1528
PFAM: Alkaline phosphatase; KEGG: yen:YE2068 alkaline phosphatase precursor; Belongs to the alkaline phosphatase family.
     
  0.900
Spro_2780
PFAM: NUDIX hydrolase; KEGG: ypi:YpsIP31758_2034 putative dATP pyrophosphohydrolase.
     
  0.900
Spro_2627
KEGG: pst:PSPTO_2579 carbonic anhydrase-related protein.
  
  
 0.829
Spro_2187
KEGG: yen:YE2164 pyruvate kinase I; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
    
  0.810
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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