STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacZPFAM: glycoside hydrolase family 42 domain 5 loop region; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: eca:ECA1490 beta-galactosidase; Belongs to the glycosyl hydrolase 2 family. (1029 aa)    
Predicted Functional Partners:
Spro_1974
PFAM: conserved hypothetical protein; KEGG: vvy:VV2643 evolved beta-D-galactosidase, beta subunit; cryptic gene.
   
 0.937
Spro_1290
Galactose mutarotase; Converts alpha-aldose to the beta-anomer.
 
 
 0.934
Spro_3103
PFAM: glycoside hydrolase family 4; KEGG: bha:BH2228 melibiase (alpha-galactosidase).
 
  
 0.924
Spro_1973
PFAM: glycoside hydrolase family 42 domain 5 loop region; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: aha:AHA_0205 evolved beta-galactosidase alpha-subunit.
  
  
 
0.918
Spro_2523
PFAM: glycoside hydrolase family 4; KEGG: mag:amb2735 alpha-galactosidase/6-phospho-beta-glucosidase.
 
  
 0.917
Spro_4225
PFAM: Aldose 1-epimerase; KEGG: ecj:JW2528 conserved hypothetical protein.
  
 
 0.916
glk
Glucokinase; KEGG: ecv:APECO1_4149 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family.
     
 0.904
xylA
KEGG: ypi:YpsIP31758_4102 xylose isomerase; TIGRFAM: xylose isomerase; PFAM: Xylose isomerase domain protein TIM barrel; Belongs to the xylose isomerase family.
    
 0.825
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.680
Spro_3229
1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: yen:YE1448 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
  
    0.670
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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