node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spro_1109 | Spro_1110 | Spro_1109 | Spro_1110 | PFAM: nitrogen regulatory protein P-II; KEGG: yen:YE3120 nitrogen regulatory protein P-II; Belongs to the P(II) protein family. | TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: yen:YE3119 probable ammonium transporter. | 0.999 |
Spro_1109 | Spro_3649 | Spro_1109 | Spro_3649 | PFAM: nitrogen regulatory protein P-II; KEGG: yen:YE3120 nitrogen regulatory protein P-II; Belongs to the P(II) protein family. | PFAM: nitrogen regulatory protein P-II; KEGG: plu:plu3309 nitrogen regulatory protein P-II.1; Belongs to the P(II) protein family. | 0.718 |
Spro_1109 | Spro_4344 | Spro_1109 | Spro_4344 | PFAM: nitrogen regulatory protein P-II; KEGG: yen:YE3120 nitrogen regulatory protein P-II; Belongs to the P(II) protein family. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | 0.591 |
Spro_1109 | Spro_4882 | Spro_1109 | Spro_4882 | PFAM: nitrogen regulatory protein P-II; KEGG: yen:YE3120 nitrogen regulatory protein P-II; Belongs to the P(II) protein family. | Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: ypi:YpsIP31758_0026 nitrogen regulation protein NR(II). | 0.803 |
Spro_1109 | glnD | Spro_1109 | Spro_3792 | PFAM: nitrogen regulatory protein P-II; KEGG: yen:YE3120 nitrogen regulatory protein P-II; Belongs to the P(II) protein family. | UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.860 |
Spro_1110 | Spro_1109 | Spro_1110 | Spro_1109 | TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: yen:YE3119 probable ammonium transporter. | PFAM: nitrogen regulatory protein P-II; KEGG: yen:YE3120 nitrogen regulatory protein P-II; Belongs to the P(II) protein family. | 0.999 |
Spro_1110 | Spro_3649 | Spro_1110 | Spro_3649 | TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: yen:YE3119 probable ammonium transporter. | PFAM: nitrogen regulatory protein P-II; KEGG: plu:plu3309 nitrogen regulatory protein P-II.1; Belongs to the P(II) protein family. | 0.996 |
Spro_1110 | Spro_4344 | Spro_1110 | Spro_4344 | TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: yen:YE3119 probable ammonium transporter. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | 0.800 |
Spro_1110 | Spro_4882 | Spro_1110 | Spro_4882 | TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: yen:YE3119 probable ammonium transporter. | Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: ypi:YpsIP31758_0026 nitrogen regulation protein NR(II). | 0.799 |
Spro_1110 | glnD | Spro_1110 | Spro_3792 | TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: yen:YE3119 probable ammonium transporter. | UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.543 |
Spro_3399 | glnD | Spro_3399 | Spro_3792 | TIGRFAM: lytic murein transglycosylase B; KEGG: eca:ECA1083 membrane-bound lytic murein transglycosylase B precursor. | UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.513 |
Spro_3649 | Spro_1109 | Spro_3649 | Spro_1109 | PFAM: nitrogen regulatory protein P-II; KEGG: plu:plu3309 nitrogen regulatory protein P-II.1; Belongs to the P(II) protein family. | PFAM: nitrogen regulatory protein P-II; KEGG: yen:YE3120 nitrogen regulatory protein P-II; Belongs to the P(II) protein family. | 0.718 |
Spro_3649 | Spro_1110 | Spro_3649 | Spro_1110 | PFAM: nitrogen regulatory protein P-II; KEGG: plu:plu3309 nitrogen regulatory protein P-II.1; Belongs to the P(II) protein family. | TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: yen:YE3119 probable ammonium transporter. | 0.996 |
Spro_3649 | Spro_4344 | Spro_3649 | Spro_4344 | PFAM: nitrogen regulatory protein P-II; KEGG: plu:plu3309 nitrogen regulatory protein P-II.1; Belongs to the P(II) protein family. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | 0.587 |
Spro_3649 | Spro_4882 | Spro_3649 | Spro_4882 | PFAM: nitrogen regulatory protein P-II; KEGG: plu:plu3309 nitrogen regulatory protein P-II.1; Belongs to the P(II) protein family. | Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: ypi:YpsIP31758_0026 nitrogen regulation protein NR(II). | 0.985 |
Spro_3649 | glnD | Spro_3649 | Spro_3792 | PFAM: nitrogen regulatory protein P-II; KEGG: plu:plu3309 nitrogen regulatory protein P-II.1; Belongs to the P(II) protein family. | UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.985 |
Spro_3649 | glnE | Spro_3649 | Spro_4290 | PFAM: nitrogen regulatory protein P-II; KEGG: plu:plu3309 nitrogen regulatory protein P-II.1; Belongs to the P(II) protein family. | (Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] | 0.405 |
Spro_4344 | Spro_1109 | Spro_4344 | Spro_1109 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | PFAM: nitrogen regulatory protein P-II; KEGG: yen:YE3120 nitrogen regulatory protein P-II; Belongs to the P(II) protein family. | 0.591 |
Spro_4344 | Spro_1110 | Spro_4344 | Spro_1110 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: yen:YE3119 probable ammonium transporter. | 0.800 |
Spro_4344 | Spro_3649 | Spro_4344 | Spro_3649 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor. | PFAM: nitrogen regulatory protein P-II; KEGG: plu:plu3309 nitrogen regulatory protein P-II.1; Belongs to the P(II) protein family. | 0.587 |