node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spro_1664 | Spro_2174 | Spro_1664 | Spro_2174 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB1384 pyruvate dehydrogenase; Belongs to the TPP enzyme family. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.909 |
Spro_1664 | Spro_2187 | Spro_1664 | Spro_2187 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB1384 pyruvate dehydrogenase; Belongs to the TPP enzyme family. | KEGG: yen:YE2164 pyruvate kinase I; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.909 |
Spro_1664 | Spro_2600 | Spro_1664 | Spro_2600 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB1384 pyruvate dehydrogenase; Belongs to the TPP enzyme family. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ypi:YpsIP31758_1808 fermentative lactate dehydrogenase. | 0.902 |
Spro_1664 | Spro_2604 | Spro_1664 | Spro_2604 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB1384 pyruvate dehydrogenase; Belongs to the TPP enzyme family. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: yen:YE2102 putative pyruvate-flavodoxin oxidoreductase. | 0.949 |
Spro_1664 | Spro_2770 | Spro_1664 | Spro_2770 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB1384 pyruvate dehydrogenase; Belongs to the TPP enzyme family. | KEGG: eca:ECA2481 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.909 |
Spro_1664 | Spro_3472 | Spro_1664 | Spro_3472 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB1384 pyruvate dehydrogenase; Belongs to the TPP enzyme family. | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: yen:YE1162 NADP-dependent malic enzyme. | 0.935 |
Spro_1664 | Spro_4011 | Spro_1664 | Spro_4011 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB1384 pyruvate dehydrogenase; Belongs to the TPP enzyme family. | 2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.904 |
Spro_1664 | dld | Spro_1664 | Spro_1364 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB1384 pyruvate dehydrogenase; Belongs to the TPP enzyme family. | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | 0.907 |
Spro_1664 | lldD | Spro_1664 | Spro_3855 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB1384 pyruvate dehydrogenase; Belongs to the TPP enzyme family. | FMN-dependent alpha-hydroxy acid dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. | 0.925 |
Spro_2174 | Spro_1664 | Spro_2174 | Spro_1664 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB1384 pyruvate dehydrogenase; Belongs to the TPP enzyme family. | 0.909 |
Spro_2174 | Spro_2187 | Spro_2174 | Spro_2187 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | KEGG: yen:YE2164 pyruvate kinase I; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.917 |
Spro_2174 | Spro_2600 | Spro_2174 | Spro_2600 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ypi:YpsIP31758_1808 fermentative lactate dehydrogenase. | 0.923 |
Spro_2174 | Spro_2604 | Spro_2174 | Spro_2604 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: yen:YE2102 putative pyruvate-flavodoxin oxidoreductase. | 0.964 |
Spro_2174 | Spro_2770 | Spro_2174 | Spro_2770 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | KEGG: eca:ECA2481 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.917 |
Spro_2174 | Spro_3472 | Spro_2174 | Spro_3472 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: yen:YE1162 NADP-dependent malic enzyme. | 0.943 |
Spro_2174 | Spro_4011 | Spro_2174 | Spro_4011 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.919 |
Spro_2174 | dld | Spro_2174 | Spro_1364 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | 0.913 |
Spro_2174 | lldD | Spro_2174 | Spro_3855 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | FMN-dependent alpha-hydroxy acid dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. | 0.918 |
Spro_2187 | Spro_1664 | Spro_2187 | Spro_1664 | KEGG: yen:YE2164 pyruvate kinase I; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB1384 pyruvate dehydrogenase; Belongs to the TPP enzyme family. | 0.909 |
Spro_2187 | Spro_2174 | Spro_2187 | Spro_2174 | KEGG: yen:YE2164 pyruvate kinase I; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.917 |