node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP59643.1 | ABP62617.1 | Ent638_0959 | Ent638_3962 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sec:SC0536 UDP-sugar hydrolase 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.902 |
ABP59643.1 | cdd | Ent638_0959 | Ent638_2746 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sec:SC0536 UDP-sugar hydrolase 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.909 |
ABP59643.1 | deoA | Ent638_0959 | Ent638_0542 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sec:SC0536 UDP-sugar hydrolase 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.925 |
ABP59643.1 | deoD | Ent638_0959 | Ent638_0544 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sec:SC0536 UDP-sugar hydrolase 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase, family 1; KEGG: spt:SPA4384 purine nucleoside phosphorylase. | 0.915 |
ABP59643.1 | surE | Ent638_0959 | Ent638_3215 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sec:SC0536 UDP-sugar hydrolase 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase / 3'-nucleotidase / exopolyphosphatase; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. | 0.919 |
ABP59643.1 | tdk | Ent638_0959 | Ent638_2305 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sec:SC0536 UDP-sugar hydrolase 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | PFAM: thymidine kinase; KEGG: sdy:SDY_1290 thymidine kinase. | 0.928 |
ABP59643.1 | upp | Ent638_0959 | Ent638_2986 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sec:SC0536 UDP-sugar hydrolase 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.901 |
ABP62447.1 | ABP62617.1 | Ent638_3792 | Ent638_3962 | N-isopropylammelide isopropylaminohydrolase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: ecj:JW0328 cytosine deaminase. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.909 |
ABP62447.1 | deoA | Ent638_3792 | Ent638_0542 | N-isopropylammelide isopropylaminohydrolase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: ecj:JW0328 cytosine deaminase. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.918 |
ABP62447.1 | deoD | Ent638_3792 | Ent638_0544 | N-isopropylammelide isopropylaminohydrolase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: ecj:JW0328 cytosine deaminase. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase, family 1; KEGG: spt:SPA4384 purine nucleoside phosphorylase. | 0.900 |
ABP62447.1 | upp | Ent638_3792 | Ent638_2986 | N-isopropylammelide isopropylaminohydrolase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: ecj:JW0328 cytosine deaminase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.932 |
ABP62617.1 | ABP59643.1 | Ent638_3962 | Ent638_0959 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sec:SC0536 UDP-sugar hydrolase 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.902 |
ABP62617.1 | ABP62447.1 | Ent638_3962 | Ent638_3792 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | N-isopropylammelide isopropylaminohydrolase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: ecj:JW0328 cytosine deaminase. | 0.909 |
ABP62617.1 | cdd | Ent638_3962 | Ent638_2746 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.983 |
ABP62617.1 | deoA | Ent638_3962 | Ent638_0542 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.962 |
ABP62617.1 | deoB | Ent638_3962 | Ent638_0543 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.733 |
ABP62617.1 | deoC | Ent638_3962 | Ent638_0541 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. | 0.629 |
ABP62617.1 | deoD | Ent638_3962 | Ent638_0544 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase, family 1; KEGG: spt:SPA4384 purine nucleoside phosphorylase. | 0.937 |
ABP62617.1 | surE | Ent638_3962 | Ent638_3215 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 5'-nucleotidase / 3'-nucleotidase / exopolyphosphatase; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. | 0.906 |
ABP62617.1 | tdk | Ent638_3962 | Ent638_2305 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | PFAM: thymidine kinase; KEGG: sdy:SDY_1290 thymidine kinase. | 0.918 |