node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP59817.1 | ABP59818.1 | Ent638_1136 | Ent638_1137 | Monosaccharide ABC transporter membrane protein, CUT2 family; PFAM: inner-membrane translocator; KEGG: eca:ECA2720 ABC transporter, permease protein; TC 3.A.1.2.-; Belongs to the binding-protein-dependent transport system permease family. | Monosaccharide ABC transporter substrate-binding protein, CUT2 family; KEGG: eca:ECA1405 putative exported protein; TC 3.A.1.2.-. | 0.939 |
ABP59817.1 | mtnK | Ent638_1136 | Ent638_1139 | Monosaccharide ABC transporter membrane protein, CUT2 family; PFAM: inner-membrane translocator; KEGG: eca:ECA2720 ABC transporter, permease protein; TC 3.A.1.2.-; Belongs to the binding-protein-dependent transport system permease family. | 5'-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.546 |
ABP59818.1 | ABP59817.1 | Ent638_1137 | Ent638_1136 | Monosaccharide ABC transporter substrate-binding protein, CUT2 family; KEGG: eca:ECA1405 putative exported protein; TC 3.A.1.2.-. | Monosaccharide ABC transporter membrane protein, CUT2 family; PFAM: inner-membrane translocator; KEGG: eca:ECA2720 ABC transporter, permease protein; TC 3.A.1.2.-; Belongs to the binding-protein-dependent transport system permease family. | 0.939 |
ABP59818.1 | ABP62479.1 | Ent638_1137 | Ent638_3824 | Monosaccharide ABC transporter substrate-binding protein, CUT2 family; KEGG: eca:ECA1405 putative exported protein; TC 3.A.1.2.-. | PFAM: protein of unknown function DUF1471; KEGG: yps:YPTB3770 hypothetical protein. | 0.722 |
ABP59818.1 | mtnA | Ent638_1137 | Ent638_1140 | Monosaccharide ABC transporter substrate-binding protein, CUT2 family; KEGG: eca:ECA1405 putative exported protein; TC 3.A.1.2.-. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.826 |
ABP59818.1 | mtnB | Ent638_1137 | Ent638_1143 | Monosaccharide ABC transporter substrate-binding protein, CUT2 family; KEGG: eca:ECA1405 putative exported protein; TC 3.A.1.2.-. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.462 |
ABP59818.1 | mtnK | Ent638_1137 | Ent638_1139 | Monosaccharide ABC transporter substrate-binding protein, CUT2 family; KEGG: eca:ECA1405 putative exported protein; TC 3.A.1.2.-. | 5'-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.753 |
ABP62479.1 | ABP59818.1 | Ent638_3824 | Ent638_1137 | PFAM: protein of unknown function DUF1471; KEGG: yps:YPTB3770 hypothetical protein. | Monosaccharide ABC transporter substrate-binding protein, CUT2 family; KEGG: eca:ECA1405 putative exported protein; TC 3.A.1.2.-. | 0.722 |
ABP62479.1 | mtnK | Ent638_3824 | Ent638_1139 | PFAM: protein of unknown function DUF1471; KEGG: yps:YPTB3770 hypothetical protein. | 5'-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.450 |
cysC | mtnC | Ent638_3221 | Ent638_1142 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Acireductone synthase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.448 |
cysC | mtnD | Ent638_3221 | Ent638_1141 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Acireductone dioxygenase apoprotein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.498 |
cysC | mtnK | Ent638_3221 | Ent638_1139 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 5'-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.456 |
cysC | mtnN | Ent638_3221 | Ent638_0699 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP [...] | 0.420 |
cysC | speD | Ent638_3221 | Ent638_0668 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | Adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.426 |
mtnA | ABP59818.1 | Ent638_1140 | Ent638_1137 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Monosaccharide ABC transporter substrate-binding protein, CUT2 family; KEGG: eca:ECA1405 putative exported protein; TC 3.A.1.2.-. | 0.826 |
mtnA | mtnB | Ent638_1140 | Ent638_1143 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.997 |
mtnA | mtnC | Ent638_1140 | Ent638_1142 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Acireductone synthase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.788 |
mtnA | mtnD | Ent638_1140 | Ent638_1141 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Acireductone dioxygenase apoprotein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.862 |
mtnA | mtnK | Ent638_1140 | Ent638_1139 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 5'-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.999 |
mtnA | speD | Ent638_1140 | Ent638_0668 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.541 |