node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP61101.1 | ABP61102.1 | Ent638_2432 | Ent638_2433 | PFAM: protein of unknown function DUF28; KEGG: ecv:APECO1_914 hypothetical protein. | Dihydroneopterin triphosphate pyrophosphatase; PFAM: NUDIX hydrolase; KEGG: stm:STM1900 dATP pyrophosphohydrolase. | 0.784 |
ABP61101.1 | ruvA | Ent638_2432 | Ent638_2430 | PFAM: protein of unknown function DUF28; KEGG: ecv:APECO1_914 hypothetical protein. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.662 |
ABP61101.1 | ruvB | Ent638_2432 | Ent638_2429 | PFAM: protein of unknown function DUF28; KEGG: ecv:APECO1_914 hypothetical protein. | Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.640 |
ABP61101.1 | ruvC | Ent638_2432 | Ent638_2431 | PFAM: protein of unknown function DUF28; KEGG: ecv:APECO1_914 hypothetical protein. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.792 |
ABP61102.1 | ABP61101.1 | Ent638_2433 | Ent638_2432 | Dihydroneopterin triphosphate pyrophosphatase; PFAM: NUDIX hydrolase; KEGG: stm:STM1900 dATP pyrophosphohydrolase. | PFAM: protein of unknown function DUF28; KEGG: ecv:APECO1_914 hypothetical protein. | 0.784 |
ABP61102.1 | ruvB | Ent638_2433 | Ent638_2429 | Dihydroneopterin triphosphate pyrophosphatase; PFAM: NUDIX hydrolase; KEGG: stm:STM1900 dATP pyrophosphohydrolase. | Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.412 |
ABP61102.1 | ruvC | Ent638_2433 | Ent638_2431 | Dihydroneopterin triphosphate pyrophosphatase; PFAM: NUDIX hydrolase; KEGG: stm:STM1900 dATP pyrophosphohydrolase. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.540 |
ABP61973.1 | polA | Ent638_3310 | Ent638_4102 | Exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: ecs:ECs3764 ssDNA exonuclease RecJ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.496 |
ABP61973.1 | recA | Ent638_3310 | Ent638_3174 | Exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: ecs:ECs3764 ssDNA exonuclease RecJ. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.426 |
ABP61973.1 | recX | Ent638_3310 | Ent638_3173 | Exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: ecs:ECs3764 ssDNA exonuclease RecJ. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.402 |
ABP61973.1 | ruvA | Ent638_3310 | Ent638_2430 | Exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: ecs:ECs3764 ssDNA exonuclease RecJ. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.435 |
ABP61973.1 | ruvB | Ent638_3310 | Ent638_2429 | Exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: ecs:ECs3764 ssDNA exonuclease RecJ. | Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.454 |
ABP61973.1 | ruvC | Ent638_3310 | Ent638_2431 | Exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: ecs:ECs3764 ssDNA exonuclease RecJ. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.556 |
ABP62671.1 | recA | Ent638_4016 | Ent638_3174 | Mg chelatase, subunit ChlI; KEGG: ecv:APECO1_2704 putative bifunctional enzyme and transcriptional regulator; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.410 |
ABP62671.1 | ruvC | Ent638_4016 | Ent638_2431 | Mg chelatase, subunit ChlI; KEGG: ecv:APECO1_2704 putative bifunctional enzyme and transcriptional regulator; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.634 |
polA | ABP61973.1 | Ent638_4102 | Ent638_3310 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: ecs:ECs3764 ssDNA exonuclease RecJ. | 0.496 |
polA | recA | Ent638_4102 | Ent638_3174 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.977 |
polA | recF | Ent638_4102 | Ent638_0003 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.540 |
polA | recX | Ent638_4102 | Ent638_3173 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.536 |
polA | ruvA | Ent638_4102 | Ent638_2430 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.480 |