node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP58892.1 | ABP58894.1 | Ent638_0202 | Ent638_0204 | Tyrosine lyase ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: sec:SC4041 deoxyxylulose-5-P + thi-S-COSH + tyrosine 4-methyl-5-(beta-hydroxyethyl)thiazole-P + 4-hydroxy-benzyl-alcohol + C1 of tyrosine. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: spt:SPA3998 thiamine biosynthesis protein. | 0.954 |
ABP58892.1 | ABP58895.1 | Ent638_0202 | Ent638_0205 | Tyrosine lyase ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: sec:SC4041 deoxyxylulose-5-P + thi-S-COSH + tyrosine 4-methyl-5-(beta-hydroxyethyl)thiazole-P + 4-hydroxy-benzyl-alcohol + C1 of tyrosine. | [sulfur carrier protein ThiS] adenylyltransferase; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: spt:SPA3999 thiamine biosynthesis protein. | 0.984 |
ABP58892.1 | ABP59566.1 | Ent638_0202 | Ent638_0882 | Tyrosine lyase ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: sec:SC4041 deoxyxylulose-5-P + thi-S-COSH + tyrosine 4-methyl-5-(beta-hydroxyethyl)thiazole-P + 4-hydroxy-benzyl-alcohol + C1 of tyrosine. | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.435 |
ABP58892.1 | ABP61375.1 | Ent638_0202 | Ent638_2710 | Tyrosine lyase ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: sec:SC4041 deoxyxylulose-5-P + thi-S-COSH + tyrosine 4-methyl-5-(beta-hydroxyethyl)thiazole-P + 4-hydroxy-benzyl-alcohol + C1 of tyrosine. | KEGG: ecv:APECO1_4442 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.634 |
ABP58892.1 | thiC | Ent638_0202 | Ent638_0207 | Tyrosine lyase ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: sec:SC4041 deoxyxylulose-5-P + thi-S-COSH + tyrosine 4-methyl-5-(beta-hydroxyethyl)thiazole-P + 4-hydroxy-benzyl-alcohol + C1 of tyrosine. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.985 |
ABP58892.1 | thiE | Ent638_0202 | Ent638_0206 | Tyrosine lyase ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: sec:SC4041 deoxyxylulose-5-P + thi-S-COSH + tyrosine 4-methyl-5-(beta-hydroxyethyl)thiazole-P + 4-hydroxy-benzyl-alcohol + C1 of tyrosine. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.982 |
ABP58892.1 | thiG | Ent638_0202 | Ent638_0203 | Tyrosine lyase ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: sec:SC4041 deoxyxylulose-5-P + thi-S-COSH + tyrosine 4-methyl-5-(beta-hydroxyethyl)thiazole-P + 4-hydroxy-benzyl-alcohol + C1 of tyrosine. | Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.999 |
ABP58892.1 | thiM | Ent638_0202 | Ent638_2711 | Tyrosine lyase ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: sec:SC4041 deoxyxylulose-5-P + thi-S-COSH + tyrosine 4-methyl-5-(beta-hydroxyethyl)thiazole-P + 4-hydroxy-benzyl-alcohol + C1 of tyrosine. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.538 |
ABP58894.1 | ABP58892.1 | Ent638_0204 | Ent638_0202 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: spt:SPA3998 thiamine biosynthesis protein. | Tyrosine lyase ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: sec:SC4041 deoxyxylulose-5-P + thi-S-COSH + tyrosine 4-methyl-5-(beta-hydroxyethyl)thiazole-P + 4-hydroxy-benzyl-alcohol + C1 of tyrosine. | 0.954 |
ABP58894.1 | ABP58895.1 | Ent638_0204 | Ent638_0205 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: spt:SPA3998 thiamine biosynthesis protein. | [sulfur carrier protein ThiS] adenylyltransferase; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: spt:SPA3999 thiamine biosynthesis protein. | 0.998 |
ABP58894.1 | ABP61375.1 | Ent638_0204 | Ent638_2710 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: spt:SPA3998 thiamine biosynthesis protein. | KEGG: ecv:APECO1_4442 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.801 |
ABP58894.1 | thiC | Ent638_0204 | Ent638_0207 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: spt:SPA3998 thiamine biosynthesis protein. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.960 |
ABP58894.1 | thiE | Ent638_0204 | Ent638_0206 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: spt:SPA3998 thiamine biosynthesis protein. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.963 |
ABP58894.1 | thiG | Ent638_0204 | Ent638_0203 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: spt:SPA3998 thiamine biosynthesis protein. | Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.997 |
ABP58894.1 | thiM | Ent638_0204 | Ent638_2711 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: spt:SPA3998 thiamine biosynthesis protein. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.509 |
ABP58895.1 | ABP58892.1 | Ent638_0205 | Ent638_0202 | [sulfur carrier protein ThiS] adenylyltransferase; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: spt:SPA3999 thiamine biosynthesis protein. | Tyrosine lyase ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: sec:SC4041 deoxyxylulose-5-P + thi-S-COSH + tyrosine 4-methyl-5-(beta-hydroxyethyl)thiazole-P + 4-hydroxy-benzyl-alcohol + C1 of tyrosine. | 0.984 |
ABP58895.1 | ABP58894.1 | Ent638_0205 | Ent638_0204 | [sulfur carrier protein ThiS] adenylyltransferase; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: spt:SPA3999 thiamine biosynthesis protein. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: spt:SPA3998 thiamine biosynthesis protein. | 0.998 |
ABP58895.1 | ABP61375.1 | Ent638_0205 | Ent638_2710 | [sulfur carrier protein ThiS] adenylyltransferase; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: spt:SPA3999 thiamine biosynthesis protein. | KEGG: ecv:APECO1_4442 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.621 |
ABP58895.1 | thiC | Ent638_0205 | Ent638_0207 | [sulfur carrier protein ThiS] adenylyltransferase; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: spt:SPA3999 thiamine biosynthesis protein. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.961 |
ABP58895.1 | thiE | Ent638_0205 | Ent638_0206 | [sulfur carrier protein ThiS] adenylyltransferase; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: spt:SPA3999 thiamine biosynthesis protein. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.975 |