STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABP61447.1PFAM: 37kDa nucleoid-associated protein; KEGG: stm:STM2226 nucleotide associated protein, present in spermidine nucleoids. (335 aa)    
Predicted Functional Partners:
ABP61449.1
PFAM: sulfatase; KEGG: spt:SPA0622 putative sulphatase.
 
   
 0.897
ABP61448.1
PFAM: protein of unknown function DUF1414; KEGG: stm:STM2227 putative cytoplasmic protein; Belongs to the UPF0352 family.
 
   
 0.767
yihI
Protein of unknown function DUF414; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.735
ABP61504.1
PFAM: protein of unknown function DUF412; KEGG: stm:STM2336 putative cytoplasmic protein.
  
     0.715
rlmM
Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
  
    0.661
ABP62026.1
PFAM: protein of unknown function DUF469; KEGG: ecv:APECO1_3562 hypothetical protein.
  
     0.613
syd
Syd family protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.
  
     0.600
ABP62672.1
PFAM: protein of unknown function DUF413; KEGG: sdy:SDY_3984 hypothetical protein.
  
     0.578
seqA
Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
    0.538
metJ
Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
    0.490
Your Current Organism:
Enterobacter sp. 638
NCBI taxonomy Id: 399742
Other names: E. sp. 638
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.