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purM protein (Enterobacter sp. 638) - STRING interaction network
"purM" - Phosphoribosylformylglycinamidine cyclo-ligase in Enterobacter sp. 638
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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purMPhosphoribosylformylglycinamidine cyclo-ligase; KEGG- sfx-S2692 phosphoribosylaminoimidazole synthetase, AIR synthetase; TIGRFAM- phosphoribosylformylglycinamidine cyclo-ligase; PFAM- AIR synthase related protein; AIR synthase related protein domain protein (345 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1295 aa)
 
  0.999
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (213 aa)
   
  0.999
purD
Phosphoribosylamine--glycine ligase; KEGG- spt-SPA4012 phosphoribosylglycineamide synthetase; TIGRFAM- phosphoribosylamine--glycine ligase; PFAM- phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family (430 aa)
 
  0.998
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family (505 aa)
   
  0.997
purE
N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (169 aa)
 
 
  0.996
purK
N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) (355 aa)
 
 
  0.990
purH
Bifunctional purine biosynthesis protein PurH; KEGG- stm-STM4176 bifunctional- phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase; TIGRFAM- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- MGS domain protein; AICARFT/IMPCHase bienzyme, formylation region (550 aa)
 
 
  0.984
purC
KEGG- sfv-SFV_2521 phosphoribosylaminoimidazole-succinocarboxamide synthetase; TIGRFAM- phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM- SAICAR synthetase (237 aa)
 
   
  0.942
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (525 aa)
 
   
  0.919
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (630 aa)
   
 
    0.804
Your Current Organism:
Enterobacter sp. 638
NCBI taxonomy Id: 399742
Other names: E. sp. 638, Enterobacter sp. 638
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