STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speBAgmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily. (306 aa)    
Predicted Functional Partners:
speA
Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine.
  
 
 0.960
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
 
 0.951
ABP59886.1
PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sec:SC0721 ornithine decarboxylase isozyme, inducible.
    
 0.911
ABP62042.1
PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: ecs:ECs3841 ornithine decarboxylase isozyme.
    
 0.911
ABP60605.1
PFAM: GCN5-related N-acetyltransferase; KEGG: ecv:APECO1_667 spermidine N1-acetyltransferase.
     
 0.904
patA
Diamine aminotransferase apoenzyme; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
   
 
  0.902
hutH
KEGG: spt:SPA1961 histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; Belongs to the PAL/histidase family.
  
  
 0.611
ABP60220.1
L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
  
 0.551
hutI
KEGG: sec:SC0785 imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3.
  
  
 0.510
argD
Succinylornithine aminotransferase apoenzyme; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.490
Your Current Organism:
Enterobacter sp. 638
NCBI taxonomy Id: 399742
Other names: E. sp. 638
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