node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP61039.1 | rlmG | Ent638_2370 | Ent638_3540 | PFAM: protein of unknown function DUF709; KEGG: stm:STM1813 putative cytoplasmic protein. | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.457 |
ABP62199.1 | ABP62200.1 | Ent638_3541 | Ent638_3542 | PFAM: protein of unknown function DUF45; KEGG: sdy:SDY_3268 hypothetical protein. | PFAM: oxidoreductase domain protein; KEGG: ssn:SSO_3118 hypothetical protein. | 0.466 |
ABP62199.1 | rlmG | Ent638_3541 | Ent638_3540 | PFAM: protein of unknown function DUF45; KEGG: sdy:SDY_3268 hypothetical protein. | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.616 |
ABP62200.1 | ABP62199.1 | Ent638_3542 | Ent638_3541 | PFAM: oxidoreductase domain protein; KEGG: ssn:SSO_3118 hypothetical protein. | PFAM: protein of unknown function DUF45; KEGG: sdy:SDY_3268 hypothetical protein. | 0.466 |
ABP62200.1 | rlmG | Ent638_3542 | Ent638_3540 | PFAM: oxidoreductase domain protein; KEGG: ssn:SSO_3118 hypothetical protein. | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.417 |
obg | rlmG | Ent638_3619 | Ent638_3540 | Small GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.493 |
obg | rplA | Ent638_3619 | Ent638_0194 | Small GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.852 |
obg | rpoB | Ent638_3619 | Ent638_0197 | Small GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.426 |
rapA | rlmG | Ent638_0606 | Ent638_3540 | SNF2-related protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.518 |
rapA | rpoB | Ent638_0606 | Ent638_0197 | SNF2-related protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.977 |
rlmG | ABP61039.1 | Ent638_3540 | Ent638_2370 | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | PFAM: protein of unknown function DUF709; KEGG: stm:STM1813 putative cytoplasmic protein. | 0.457 |
rlmG | ABP62199.1 | Ent638_3540 | Ent638_3541 | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | PFAM: protein of unknown function DUF45; KEGG: sdy:SDY_3268 hypothetical protein. | 0.616 |
rlmG | ABP62200.1 | Ent638_3540 | Ent638_3542 | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | PFAM: oxidoreductase domain protein; KEGG: ssn:SSO_3118 hypothetical protein. | 0.417 |
rlmG | obg | Ent638_3540 | Ent638_3619 | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Small GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.493 |
rlmG | rapA | Ent638_3540 | Ent638_0606 | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | SNF2-related protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.518 |
rlmG | rlmL | Ent638_3540 | Ent638_1460 | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.473 |
rlmG | rplA | Ent638_3540 | Ent638_0194 | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.414 |
rlmG | rpoB | Ent638_3540 | Ent638_0197 | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.411 |
rlmG | rsmF | Ent638_3540 | Ent638_2405 | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 16S rRNA m(5)C-1407 methyltransferase; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.425 |
rlmG | uppS | Ent638_3540 | Ent638_0712 | 23S rRNA m(2)G-1835 methyltransferase / 16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.422 |