node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP59806.1 | ABP60639.1 | Ent638_1125 | Ent638_1963 | TIGRFAM: isochorismate synthase; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: ecv:APECO1_1456 isochorismate synthase. | PFAM: Pyrrolo-quinoline quinone; KEGG: pfl:PFL_5668 quinate/shikimate dehydrogenase, putative. | 0.800 |
ABP59806.1 | aroC | Ent638_1125 | Ent638_2877 | TIGRFAM: isochorismate synthase; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: ecv:APECO1_1456 isochorismate synthase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.911 |
ABP59806.1 | aroE | Ent638_1125 | Ent638_3713 | TIGRFAM: isochorismate synthase; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: ecv:APECO1_1456 isochorismate synthase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.882 |
ABP59806.1 | aroK | Ent638_1125 | Ent638_3803 | TIGRFAM: isochorismate synthase; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: ecv:APECO1_1456 isochorismate synthase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.418 |
ABP59806.1 | aroL | Ent638_1125 | Ent638_0859 | TIGRFAM: isochorismate synthase; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: ecv:APECO1_1456 isochorismate synthase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. | 0.494 |
ABP59806.1 | aroQ | Ent638_1125 | Ent638_3692 | TIGRFAM: isochorismate synthase; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: ecv:APECO1_1456 isochorismate synthase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.830 |
ABP59806.1 | menF | Ent638_1125 | Ent638_2815 | TIGRFAM: isochorismate synthase; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: ecv:APECO1_1456 isochorismate synthase. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.935 |
ABP60639.1 | ABP59806.1 | Ent638_1963 | Ent638_1125 | PFAM: Pyrrolo-quinoline quinone; KEGG: pfl:PFL_5668 quinate/shikimate dehydrogenase, putative. | TIGRFAM: isochorismate synthase; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: ecv:APECO1_1456 isochorismate synthase. | 0.800 |
ABP60639.1 | aroB | Ent638_1963 | Ent638_3802 | PFAM: Pyrrolo-quinoline quinone; KEGG: pfl:PFL_5668 quinate/shikimate dehydrogenase, putative. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.900 |
ABP60639.1 | aroE | Ent638_1963 | Ent638_3713 | PFAM: Pyrrolo-quinoline quinone; KEGG: pfl:PFL_5668 quinate/shikimate dehydrogenase, putative. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.900 |
ABP60639.1 | aroK | Ent638_1963 | Ent638_3803 | PFAM: Pyrrolo-quinoline quinone; KEGG: pfl:PFL_5668 quinate/shikimate dehydrogenase, putative. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.900 |
ABP60639.1 | aroL | Ent638_1963 | Ent638_0859 | PFAM: Pyrrolo-quinoline quinone; KEGG: pfl:PFL_5668 quinate/shikimate dehydrogenase, putative. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. | 0.900 |
ABP60639.1 | aroQ | Ent638_1963 | Ent638_3692 | PFAM: Pyrrolo-quinoline quinone; KEGG: pfl:PFL_5668 quinate/shikimate dehydrogenase, putative. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.900 |
ABP60639.1 | menF | Ent638_1963 | Ent638_2815 | PFAM: Pyrrolo-quinoline quinone; KEGG: pfl:PFL_5668 quinate/shikimate dehydrogenase, putative. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.800 |
aroA | aroB | Ent638_1428 | Ent638_3802 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.986 |
aroA | aroC | Ent638_1428 | Ent638_2877 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.994 |
aroA | aroE | Ent638_1428 | Ent638_3713 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.986 |
aroA | aroK | Ent638_1428 | Ent638_3803 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.978 |
aroA | aroL | Ent638_1428 | Ent638_0859 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. | 0.980 |
aroA | aroQ | Ent638_1428 | Ent638_3692 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.435 |