node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP62647.1 | wecB | Ent638_3992 | Ent638_4000 | Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: stm:STM3930 putative APC family, amino-acid transport protein, permease protein; TC 2.A.3. | UDP-N-Acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | 0.533 |
ABP62647.1 | wecC | Ent638_3992 | Ent638_3999 | Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: stm:STM3930 putative APC family, amino-acid transport protein, permease protein; TC 2.A.3. | UDP-glucose/GDP-mannose dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. | 0.549 |
ABP62647.1 | wecD | Ent638_3992 | Ent638_3998 | Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: stm:STM3930 putative APC family, amino-acid transport protein, permease protein; TC 2.A.3. | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.500 |
ABP62647.1 | wecE | Ent638_3992 | Ent638_3997 | Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: stm:STM3930 putative APC family, amino-acid transport protein, permease protein; TC 2.A.3. | TDP-4-keto-6-deoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. | 0.488 |
ABP62647.1 | wecF | Ent638_3992 | Ent638_3995 | Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: stm:STM3930 putative APC family, amino-acid transport protein, permease protein; TC 2.A.3. | 4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.542 |
ABP62647.1 | wecG | Ent638_3992 | Ent638_3993 | Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: stm:STM3930 putative APC family, amino-acid transport protein, permease protein; TC 2.A.3. | Glycosyl transferase, WecB/TagA/CpsF family; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. | 0.537 |
ABP62647.1 | wzxE | Ent638_3992 | Ent638_3996 | Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: stm:STM3930 putative APC family, amino-acid transport protein, permease protein; TC 2.A.3. | Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.470 |
ABP62647.1 | wzyE | Ent638_3992 | Ent638_3994 | Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: stm:STM3930 putative APC family, amino-acid transport protein, permease protein; TC 2.A.3. | WzyE family protein; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.444 |
ABP62647.1 | wzzE | Ent638_3992 | Ent638_4001 | Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: stm:STM3930 putative APC family, amino-acid transport protein, permease protein; TC 2.A.3. | Lipopolysaccharide biosynthesis protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. | 0.418 |
wecA | wecB | Ent638_4002 | Ent638_4000 | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). | UDP-N-Acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | 0.970 |
wecA | wecC | Ent638_4002 | Ent638_3999 | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). | UDP-glucose/GDP-mannose dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. | 0.920 |
wecA | wecD | Ent638_4002 | Ent638_3998 | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.713 |
wecA | wecE | Ent638_4002 | Ent638_3997 | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). | TDP-4-keto-6-deoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. | 0.724 |
wecA | wecF | Ent638_4002 | Ent638_3995 | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). | 4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.727 |
wecA | wecG | Ent638_4002 | Ent638_3993 | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). | Glycosyl transferase, WecB/TagA/CpsF family; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. | 0.916 |
wecA | wzxE | Ent638_4002 | Ent638_3996 | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). | Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.760 |
wecA | wzyE | Ent638_4002 | Ent638_3994 | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). | WzyE family protein; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.749 |
wecA | wzzE | Ent638_4002 | Ent638_4001 | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). | Lipopolysaccharide biosynthesis protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. | 0.942 |
wecB | ABP62647.1 | Ent638_4000 | Ent638_3992 | UDP-N-Acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: stm:STM3930 putative APC family, amino-acid transport protein, permease protein; TC 2.A.3. | 0.533 |
wecB | wecA | Ent638_4000 | Ent638_4002 | UDP-N-Acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). | 0.970 |