node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABR70423.1 | ABR71769.1 | Mmwyl1_1494 | Mmwyl1_2857 | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: afm:Afu5g06160 5-proFAR isomerase; Belongs to the HisA/HisF family. | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: hch:HCH_04980 3-phosphoshikimate 1-carboxyvinyltransferase. | 0.456 |
ABR70423.1 | ABR71770.1 | Mmwyl1_1494 | Mmwyl1_2858 | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: afm:Afu5g06160 5-proFAR isomerase; Belongs to the HisA/HisF family. | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: maq:Maqu_1023 chorismate mutase. | 0.458 |
ABR70423.1 | hisB | Mmwyl1_1494 | Mmwyl1_0753 | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: afm:Afu5g06160 5-proFAR isomerase; Belongs to the HisA/HisF family. | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: pau:PA14_67930 imidazoleglycerol-phosphate dehydratase. | 0.935 |
ABR70423.1 | hisC | Mmwyl1_1494 | Mmwyl1_1133 | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: afm:Afu5g06160 5-proFAR isomerase; Belongs to the HisA/HisF family. | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: azo:azo3348 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.917 |
ABR70423.1 | hisD | Mmwyl1_1494 | Mmwyl1_2406 | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: afm:Afu5g06160 5-proFAR isomerase; Belongs to the HisA/HisF family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.935 |
ABR70423.1 | hisF | Mmwyl1_1494 | Mmwyl1_0751 | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: afm:Afu5g06160 5-proFAR isomerase; Belongs to the HisA/HisF family. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.993 |
ABR70423.1 | hisG | Mmwyl1_1494 | Mmwyl1_2407 | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: afm:Afu5g06160 5-proFAR isomerase; Belongs to the HisA/HisF family. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.935 |
ABR70423.1 | hisH | Mmwyl1_1494 | Mmwyl1_0752 | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: afm:Afu5g06160 5-proFAR isomerase; Belongs to the HisA/HisF family. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.994 |
ABR71769.1 | ABR70423.1 | Mmwyl1_2857 | Mmwyl1_1494 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: hch:HCH_04980 3-phosphoshikimate 1-carboxyvinyltransferase. | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: afm:Afu5g06160 5-proFAR isomerase; Belongs to the HisA/HisF family. | 0.456 |
ABR71769.1 | ABR71770.1 | Mmwyl1_2857 | Mmwyl1_2858 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: hch:HCH_04980 3-phosphoshikimate 1-carboxyvinyltransferase. | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: maq:Maqu_1023 chorismate mutase. | 0.999 |
ABR71769.1 | ABR71914.1 | Mmwyl1_2857 | Mmwyl1_3003 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: hch:HCH_04980 3-phosphoshikimate 1-carboxyvinyltransferase. | PFAM: prephenate dehydratase; KEGG: hch:HCH_06095 prephenate dehydratase. | 0.964 |
ABR71769.1 | ABR72810.1 | Mmwyl1_2857 | Mmwyl1_3913 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: hch:HCH_04980 3-phosphoshikimate 1-carboxyvinyltransferase. | PFAM: Xylose isomerase domain protein TIM barrel; KEGG: csa:Csal_0292 4-hydroxyphenylpyruvate dioxygenase. | 0.452 |
ABR71769.1 | hisB | Mmwyl1_2857 | Mmwyl1_0753 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: hch:HCH_04980 3-phosphoshikimate 1-carboxyvinyltransferase. | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: pau:PA14_67930 imidazoleglycerol-phosphate dehydratase. | 0.404 |
ABR71769.1 | hisC | Mmwyl1_2857 | Mmwyl1_1133 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: hch:HCH_04980 3-phosphoshikimate 1-carboxyvinyltransferase. | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: azo:azo3348 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.992 |
ABR71769.1 | hisD | Mmwyl1_2857 | Mmwyl1_2406 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: hch:HCH_04980 3-phosphoshikimate 1-carboxyvinyltransferase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.507 |
ABR71769.1 | hisG | Mmwyl1_2857 | Mmwyl1_2407 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: hch:HCH_04980 3-phosphoshikimate 1-carboxyvinyltransferase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.535 |
ABR71770.1 | ABR70423.1 | Mmwyl1_2858 | Mmwyl1_1494 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: maq:Maqu_1023 chorismate mutase. | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: afm:Afu5g06160 5-proFAR isomerase; Belongs to the HisA/HisF family. | 0.458 |
ABR71770.1 | ABR71769.1 | Mmwyl1_2858 | Mmwyl1_2857 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: maq:Maqu_1023 chorismate mutase. | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: hch:HCH_04980 3-phosphoshikimate 1-carboxyvinyltransferase. | 0.999 |
ABR71770.1 | ABR71914.1 | Mmwyl1_2858 | Mmwyl1_3003 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: maq:Maqu_1023 chorismate mutase. | PFAM: prephenate dehydratase; KEGG: hch:HCH_06095 prephenate dehydratase. | 0.933 |
ABR71770.1 | ABR72810.1 | Mmwyl1_2858 | Mmwyl1_3913 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: maq:Maqu_1023 chorismate mutase. | PFAM: Xylose isomerase domain protein TIM barrel; KEGG: csa:Csal_0292 4-hydroxyphenylpyruvate dioxygenase. | 0.427 |