STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV84712.1TIGRFAM: DNA ligase I, ATP-dependent Dnl1; KEGG: aca:ACP_2652 DNA ligase, ATP-dependent; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein. (630 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.987
ADV83850.1
TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain; KEGG: tle:Tlet_0486 DNA polymerase III, beta subunit; SMART: DNA polymerase III beta chain.
   
 0.972
ADV84968.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.972
gpmI
Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.944
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
    
 0.925
ADV82903.1
KEGG: bge:BC1002_1278 WD40 repeat, subgroup; PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat-containing protein.
  
 0.917
ADV83068.1
PFAM: WD40 repeat, subgroup; KEGG: cci:CC1G_15653 HNWD3.
   
 0.914
ADV84505.1
PFAM: metallophosphoesterase; KEGG: azl:AZL_004740 phosphoesterase.
  
 0.887
ADV83749.1
KEGG: aca:ACP_1624 PHP domain protein; PFAM: PHP domain protein; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein.
  
 0.874
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.801
Your Current Organism:
Terriglobus saanensis
NCBI taxonomy Id: 401053
Other names: Acidobacterium sp. SP1PR4, T. saanensis SP1PR4, Terriglobus saanensis SP1PR4, Terriglobus saanensis str. SP1PR4, Terriglobus saanensis strain SP1PR4, Terriglobus sp. SP1PR4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.