node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FP0207 | FP0228 | FP0207 | FP0228 | Probable arylformamidase. | Tryptophan 2,3-dioxygenase. | 0.991 |
FP0207 | FP1036 | FP0207 | FP1036 | Probable arylformamidase. | Protein of unknown function. | 0.412 |
FP0207 | haaO | FP0207 | FP2235 | Probable arylformamidase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.511 |
FP0207 | kmo | FP0207 | FP2212 | Probable arylformamidase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.964 |
FP0207 | kynU | FP0207 | FP2215 | Probable arylformamidase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.991 |
FP0228 | FP0207 | FP0228 | FP0207 | Tryptophan 2,3-dioxygenase. | Probable arylformamidase. | 0.991 |
FP0228 | FP1036 | FP0228 | FP1036 | Tryptophan 2,3-dioxygenase. | Protein of unknown function. | 0.513 |
FP0228 | haaO | FP0228 | FP2235 | Tryptophan 2,3-dioxygenase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.678 |
FP0228 | kmo | FP0228 | FP2212 | Tryptophan 2,3-dioxygenase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.601 |
FP0228 | kynU | FP0228 | FP2215 | Tryptophan 2,3-dioxygenase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.990 |
FP1036 | FP0207 | FP1036 | FP0207 | Protein of unknown function. | Probable arylformamidase. | 0.412 |
FP1036 | FP0228 | FP1036 | FP0228 | Protein of unknown function. | Tryptophan 2,3-dioxygenase. | 0.513 |
FP1036 | haaO | FP1036 | FP2235 | Protein of unknown function. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.690 |
FP1036 | kmo | FP1036 | FP2212 | Protein of unknown function. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.609 |
FP1036 | kynU | FP1036 | FP2215 | Protein of unknown function. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.470 |
crtZ | idi | FP1451 | FP1792 | Carotene hydroxylase. | Isopentenyl-diphosphate delta-isomerase. | 0.552 |
crtZ | kmo | FP1451 | FP2212 | Carotene hydroxylase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.678 |
crtZ | paaE | FP1451 | FP2468 | Carotene hydroxylase. | Probable phenylacetic acid degradation NADH oxidoreductase PaaE. | 0.483 |
haaO | FP0207 | FP2235 | FP0207 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | Probable arylformamidase. | 0.511 |
haaO | FP0228 | FP2235 | FP0228 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | Tryptophan 2,3-dioxygenase. | 0.678 |