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dapF protein (Ralstonia pickettii 12J) - STRING interaction network
"dapF" - Diaminopimelate epimerase in Ralstonia pickettii 12J
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (292 aa)    
Predicted Functional Partners:
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (423 aa)
 
 
  0.972
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily (514 aa)
 
 
  0.963
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily (386 aa)
       
  0.957
carB
TIGRFAM- carbamoyl-phosphate synthase, large subunit; PFAM- ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG- rso-RSc1521 carbamoyl phosphate synthase large subunit; Belongs to the CarB family (1081 aa)
 
   
  0.921
Rpic_0987
4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (294 aa)
 
   
  0.839
dapB
4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family (263 aa)
 
   
  0.822
Rpic_0664
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family (370 aa)
 
   
  0.741
Rpic_0038
PFAM- lipid A biosynthesis acyltransferase; KEGG- rso-RSc0136 lipid A biosynthesis lauroyl acyltransferase (297 aa)
   
        0.737
Rpic_1012
Aspartokinase; KEGG- rso-RSc1171 aspartate kinase; TIGRFAM- aspartate kinase; aspartate kinase, monofunctional class; PFAM- aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family (416 aa)
 
   
  0.717
Rpic_0037
PFAM- lipid A biosynthesis acyltransferase; KEGG- rso-RSc0135 lipid A biosynthesis lauroyl acyltransferase (282 aa)
   
        0.717
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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