STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rpic_1003TIGRFAM: serine O-acetyltransferase; KEGG: rso:RSc1162 probable O-acetylserine synthase (serine acetyltransferase) protein. (248 aa)    
Predicted Functional Partners:
Rpic_0787
TIGRFAM: cysteine synthase; cysteine synthase B; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rso:RSc0917 cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.996
cysS
KEGG: rso:RSc1167 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.975
Rpic_3490
L-serine dehydratase 1; KEGG: rso:RSc3296 probable L-serine dehydratase (L-serine deaminase) protein; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.917
Rpic_1202
PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: rso:RSc1327 homoserine dehydrogenase.
  
  
 0.862
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.859
Rpic_1906
KEGG: rso:RSc1640 putative phosphoserine phosphatase protein; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3.
    
 0.843
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.819
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.816
ilvA
Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
 0.811
Rpic_0819
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rso:RSc0948 hypothetical protein.
    
 0.811
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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