STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rpic_3494PFAM: sodium/hydrogen exchanger; KEGG: rso:RSc3299 hypothetical protein. (407 aa)    
Predicted Functional Partners:
Rpic_3493
Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
 
     0.909
Rpic_0153
KEGG: rso:RSc0299 putative proline-rich signal peptide protein.
  
     0.714
Rpic_3081
KEGG: rso:RSc2836 hypothetical protein.
  
     0.709
Rpic_2596
PFAM: protein of unknown function DUF490; KEGG: rso:RSc2383 putative signal peptide protein.
  
     0.701
Rpic_1271
ZipA FtsZ-binding region; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.700
Rpic_0800
KEGG: rso:RSc0929 probable transmembrane protein.
 
     0.696
Rpic_0921
PFAM: Anti sigma-E protein RseA family protein; KEGG: rso:RSc1056 putative transmembrane sigma-E factor negative regulatory transcription regulator protein.
  
     0.694
Rpic_0650
KEGG: rso:RSc0700 probable transmembrane protein.
  
     0.686
Rpic_2719
PFAM: MscS Mechanosensitive ion channel; KEGG: rso:RSc2451 hypothetical protein.
 
   
 0.667
Rpic_3063
PFAM: Protein of unknown function CNP1-like; KEGG: rso:RSc2818 putative lipoprotein.
  
     0.655
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.