STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rpic_4618Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (311 aa)    
Predicted Functional Partners:
Rpic_4617
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 0.998
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.982
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.982
Rpic_4619
KEGG: reu:Reut_B5692 4-oxalocrotonate decarboxylase; TIGRFAM: 4-oxalocrotonate decarboxylase; PFAM: Hydratase/decarboxylase.
 
  
 0.974
Rpic_4620
2-oxopent-4-enoate hydratase; KEGG: reu:Reut_B5691 4-oxalocrotonate decarboxylase; TIGRFAM: 2-oxopent-4-enoate hydratase; PFAM: Hydratase/decarboxylase.
 
  
 0.969
Rpic_2498
PFAM: Aldehyde Dehydrogenase_; KEGG: rme:Rmet_5128 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.909
Rpic_1338
PFAM: Aldehyde Dehydrogenase_; KEGG: rso:RSc1456 putative betaine aldehyde dehydrogenase (BADH) oxidoreductase protein; Belongs to the aldehyde dehydrogenase family.
    
 0.907
Rpic_2566
PFAM: Aldehyde Dehydrogenase_; KEGG: rso:RSc2350 probable aldehyde dehydrogenase oxidoreductase protein; Belongs to the aldehyde dehydrogenase family.
    
 0.907
Rpic_3031
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
     
 0.907
Rpic_1955
2-oxo-hepta-3-ene-1,7-dioic acid hydratase; KEGG: bur:Bcep18194_B1778 4-oxalocrotonate decarboxylase; TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase.
 
  
 0.906
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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