STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABO34407.1Aldehyde dehydrogenase; Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate. (465 aa)    
Predicted Functional Partners:
fucA
Class II aldolase/adducin family protein; Involved in the biosynthesis of the coenzyme F420 which requires phospholactate produced via the aldol cleavage of L-fuculose 1-phosphate and the NAD(+)-dependent oxidation of (S)-lactaldehyde. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and S-lactaldehyde.
  
 
 0.900
ABO35169.1
phenylacetate-CoA ligase; KEGG: mmp:MMP0715 coenzyme F390 synthetase II.
  
 
 0.877
ABO35658.1
phenylacetate-CoA ligase; KEGG: mmp:MMP0314 coenzyme F390 synthetase.
  
 
 0.877
ABO35812.1
phenylacetate-CoA ligase; KEGG: mmp:MMP0160 coenzyme F390 synthetase.
  
 
 0.877
ABO35346.1
PFAM: AMP-dependent synthetase and ligase; KEGG: mmp:MMP0566 acyl-CoA synthase.
  
 
 0.872
ABO34793.1
KEGG: mmp:MMP1105 succinate-CoA ligase (ADP-forming), beta chain; TIGRFAM: succinyl-CoA synthetase, beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein.
 
 
 0.848
ABO35518.1
Cytidine kinase / inosine-guanosine kinase; PFAM: PfkB domain protein; KEGG: mmp:MMP0418 carbohydrate kinase, PfkB; Belongs to the carbohydrate kinase PfkB family.
  
 
 0.837
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 
 0.824
argD
TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: mmp:MMP1101 aminotransferase (subgroup II) similar to acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
 0.822
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.818
Your Current Organism:
Methanococcus maripaludis C5
NCBI taxonomy Id: 402880
Other names: M. maripaludis C5, Methanococcus maripaludis str. C5, Methanococcus maripaludis strain C5
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