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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cbiACobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (447 aa)    
Predicted Functional Partners:
ABO35641.1
PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: mmp:MMP0330 precorrin-8X methylmutase CbiC/CobH.
 
 0.997
ABO35653.1
TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0319 precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.
  
 0.984
cbiT
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
  
 0.969
ABO35130.1
Cobaltochelatase CobN subunit; PFAM: CobN/magnesium chelatase; KEGG: mac:MA0348 protoporphyrin IX magnesium chelatase.
 
 
 0.964
ABO35778.1
Cobaltochelatase CobN subunit; PFAM: CobN/magnesium chelatase; KEGG: mmp:MMP0493 cobaltochelatase.
 
 
 0.964
cobQ
Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.950
cobD
Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
 0.949
ABO36044.1
KEGG: mmp:MMP1662 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
  
 0.937
ABO35070.1
TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0953 precorrin-3B C17-methyltransferase.
 
  
 0.936
ABO36115.1
PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: mmp:MMP1591 cobalamin (vitamin B12) biosynthesis CbiG protein.
 
  
 0.921
Your Current Organism:
Methanococcus maripaludis C5
NCBI taxonomy Id: 402880
Other names: M. maripaludis C5, Methanococcus maripaludis str. C5, Methanococcus maripaludis strain C5
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