node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABO34680.1 | ABO35070.1 | MmarC5_0364 | MmarC5_0760 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP1227 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0953 precorrin-3B C17-methyltransferase. | 0.963 |
ABO34680.1 | ABO35313.1 | MmarC5_0364 | MmarC5_1007 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP1227 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase. | TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: mmp:MMP0599 precorrin-6x reductase CbiJ/CobK. | 0.966 |
ABO34680.1 | ABO35641.1 | MmarC5_0364 | MmarC5_1343 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP1227 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: mmp:MMP0330 precorrin-8X methylmutase CbiC/CobH. | 0.999 |
ABO34680.1 | ABO35653.1 | MmarC5_0364 | MmarC5_1355 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP1227 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0319 precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family. | 0.948 |
ABO34680.1 | ABO36044.1 | MmarC5_0364 | MmarC5_1747 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP1227 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase. | KEGG: mmp:MMP1662 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.944 |
ABO34680.1 | ABO36115.1 | MmarC5_0364 | MmarC5_1818 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP1227 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase. | PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: mmp:MMP1591 cobalamin (vitamin B12) biosynthesis CbiG protein. | 0.986 |
ABO34680.1 | cbiA | MmarC5_0364 | MmarC5_0100 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP1227 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase. | Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. | 0.919 |
ABO34680.1 | cbiD | MmarC5_0364 | MmarC5_0387 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP1227 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.986 |
ABO34680.1 | cbiT | MmarC5_0364 | MmarC5_0369 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP1227 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase. | precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. | 0.997 |
ABO34680.1 | cobS | MmarC5_0364 | MmarC5_0745 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP1227 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.789 |
ABO35070.1 | ABO34680.1 | MmarC5_0760 | MmarC5_0364 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0953 precorrin-3B C17-methyltransferase. | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP1227 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase. | 0.963 |
ABO35070.1 | ABO35313.1 | MmarC5_0760 | MmarC5_1007 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0953 precorrin-3B C17-methyltransferase. | TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: mmp:MMP0599 precorrin-6x reductase CbiJ/CobK. | 0.998 |
ABO35070.1 | ABO35641.1 | MmarC5_0760 | MmarC5_1343 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0953 precorrin-3B C17-methyltransferase. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: mmp:MMP0330 precorrin-8X methylmutase CbiC/CobH. | 0.997 |
ABO35070.1 | ABO35653.1 | MmarC5_0760 | MmarC5_1355 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0953 precorrin-3B C17-methyltransferase. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0319 precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family. | 0.996 |
ABO35070.1 | ABO36044.1 | MmarC5_0760 | MmarC5_1747 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0953 precorrin-3B C17-methyltransferase. | KEGG: mmp:MMP1662 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.999 |
ABO35070.1 | ABO36115.1 | MmarC5_0760 | MmarC5_1818 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0953 precorrin-3B C17-methyltransferase. | PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: mmp:MMP1591 cobalamin (vitamin B12) biosynthesis CbiG protein. | 0.997 |
ABO35070.1 | cbiA | MmarC5_0760 | MmarC5_0100 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0953 precorrin-3B C17-methyltransferase. | Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. | 0.936 |
ABO35070.1 | cbiD | MmarC5_0760 | MmarC5_0387 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0953 precorrin-3B C17-methyltransferase. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.972 |
ABO35070.1 | cbiT | MmarC5_0760 | MmarC5_0369 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0953 precorrin-3B C17-methyltransferase. | precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. | 0.972 |
ABO35070.1 | cobS | MmarC5_0760 | MmarC5_0745 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0953 precorrin-3B C17-methyltransferase. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.964 |