node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABO35104.1 | guaAA | MmarC5_0794 | MmarC5_0133 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. | 0.872 |
ABO35104.1 | guaAB | MmarC5_0794 | MmarC5_0702 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.910 |
ABO35104.1 | guaB | MmarC5_0794 | MmarC5_1545 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.949 |
ABO35104.1 | hpt | MmarC5_0794 | MmarC5_1530 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.976 |
ABO35104.1 | purA | MmarC5_0794 | MmarC5_0146 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.999 |
ABO35104.1 | pyrF | MmarC5_0794 | MmarC5_1004 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.803 |
ABO35104.1 | pyrH | MmarC5_0794 | MmarC5_1253 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.640 |
ABO35104.1 | surE | MmarC5_0794 | MmarC5_0542 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.952 |
ABO35104.1 | tmk | MmarC5_0794 | MmarC5_0559 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | dTMP kinase; PFAM: thymidylate kinase; KEGG: mmp:MMP1034 thymidylate kinase. | 0.645 |
ABO35104.1 | upp | MmarC5_0794 | MmarC5_0896 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.502 |
guaAA | ABO35104.1 | MmarC5_0133 | MmarC5_0794 | GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.872 |
guaAA | guaAB | MmarC5_0133 | MmarC5_0702 | GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.998 |
guaAA | guaB | MmarC5_0133 | MmarC5_1545 | GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.994 |
guaAA | hpt | MmarC5_0133 | MmarC5_1530 | GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.947 |
guaAA | purA | MmarC5_0133 | MmarC5_0146 | GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.940 |
guaAA | pyrF | MmarC5_0133 | MmarC5_1004 | GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.711 |
guaAA | pyrH | MmarC5_0133 | MmarC5_1253 | GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. | Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.704 |
guaAA | surE | MmarC5_0133 | MmarC5_0542 | GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. | 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.955 |
guaAA | upp | MmarC5_0133 | MmarC5_0896 | GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.586 |
guaAB | ABO35104.1 | MmarC5_0702 | MmarC5_0794 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.910 |