node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABO35104.1 | guaAB | MmarC5_0794 | MmarC5_0702 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.910 |
ABO35104.1 | purA | MmarC5_0794 | MmarC5_0146 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.999 |
ABO35104.1 | purC | MmarC5_0794 | MmarC5_1067 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: mmp:MMP0540 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.999 |
ABO35104.1 | purD | MmarC5_0794 | MmarC5_1246 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: mmp:MMP0392 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | 0.989 |
ABO35104.1 | purE | MmarC5_0794 | MmarC5_1391 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.978 |
ABO35104.1 | purF | MmarC5_0794 | MmarC5_0439 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.993 |
ABO35104.1 | purL | MmarC5_0794 | MmarC5_1496 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.982 |
ABO35104.1 | purM | MmarC5_0794 | MmarC5_0337 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: mmp:MMP1254 phosphoribosylaminoimidazole synthetase. | 0.981 |
ABO35104.1 | purQ | MmarC5_0794 | MmarC5_1497 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.977 |
ABO35104.1 | purT | MmarC5_0794 | MmarC5_1555 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Formate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.805 |
guaAB | ABO35104.1 | MmarC5_0702 | MmarC5_0794 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.910 |
guaAB | purA | MmarC5_0702 | MmarC5_0146 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.867 |
guaAB | purC | MmarC5_0702 | MmarC5_1067 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | KEGG: mmp:MMP0540 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.845 |
guaAB | purD | MmarC5_0702 | MmarC5_1246 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | KEGG: mmp:MMP0392 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | 0.893 |
guaAB | purE | MmarC5_0702 | MmarC5_1391 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.669 |
guaAB | purF | MmarC5_0702 | MmarC5_0439 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.800 |
guaAB | purL | MmarC5_0702 | MmarC5_1496 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.919 |
guaAB | purM | MmarC5_0702 | MmarC5_0337 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: mmp:MMP1254 phosphoribosylaminoimidazole synthetase. | 0.780 |
guaAB | purQ | MmarC5_0702 | MmarC5_1497 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.813 |
purA | ABO35104.1 | MmarC5_0146 | MmarC5_0794 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mmp:MMP0971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.999 |