node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABO34875.1 | ABO34955.1 | MmarC5_0561 | MmarC5_0643 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | MCM family protein; PFAM: magnesium chelatase, ChlI subunit; MCM family protein; KEGG: mmp:MMP0030 DNA replication protein; MCM family; putative; Belongs to the MCM family. | 0.913 |
ABO34875.1 | ABO35420.1 | MmarC5_0561 | MmarC5_1119 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | Replicative DNA helicase Mcm; PFAM: magnesium chelatase, ChlI subunit; MCM family protein; KEGG: mmp:MMP0470 MCM family related protein; Belongs to the MCM family. | 0.926 |
ABO34875.1 | ABO35556.1 | MmarC5_0561 | MmarC5_1258 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | KEGG: mmp:MMP0380 DNA polymerase family B; TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | 0.926 |
ABO34875.1 | ABO35853.1 | MmarC5_0561 | MmarC5_1556 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | KEGG: mmp:MMP0122 hypothetical protein. | 0.653 |
ABO34875.1 | fen | MmarC5_0561 | MmarC5_0280 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.722 |
ABO34875.1 | lig | MmarC5_0561 | MmarC5_0793 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.756 |
ABO34875.1 | pcn | MmarC5_0561 | MmarC5_1695 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | Monomeric archaeal DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.968 |
ABO34875.1 | polB | MmarC5_0561 | MmarC5_1676 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | DNA polymerase II small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.811 |
ABO34875.1 | priS | MmarC5_0561 | MmarC5_1606 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.834 |
ABO34875.1 | rfcS | MmarC5_0561 | MmarC5_1210 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.911 |
ABO34955.1 | ABO34875.1 | MmarC5_0643 | MmarC5_0561 | MCM family protein; PFAM: magnesium chelatase, ChlI subunit; MCM family protein; KEGG: mmp:MMP0030 DNA replication protein; MCM family; putative; Belongs to the MCM family. | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | 0.913 |
ABO34955.1 | ABO35556.1 | MmarC5_0643 | MmarC5_1258 | MCM family protein; PFAM: magnesium chelatase, ChlI subunit; MCM family protein; KEGG: mmp:MMP0030 DNA replication protein; MCM family; putative; Belongs to the MCM family. | KEGG: mmp:MMP0380 DNA polymerase family B; TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | 0.965 |
ABO34955.1 | ABO35853.1 | MmarC5_0643 | MmarC5_1556 | MCM family protein; PFAM: magnesium chelatase, ChlI subunit; MCM family protein; KEGG: mmp:MMP0030 DNA replication protein; MCM family; putative; Belongs to the MCM family. | KEGG: mmp:MMP0122 hypothetical protein. | 0.913 |
ABO34955.1 | fen | MmarC5_0643 | MmarC5_0280 | MCM family protein; PFAM: magnesium chelatase, ChlI subunit; MCM family protein; KEGG: mmp:MMP0030 DNA replication protein; MCM family; putative; Belongs to the MCM family. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.850 |
ABO34955.1 | lig | MmarC5_0643 | MmarC5_0793 | MCM family protein; PFAM: magnesium chelatase, ChlI subunit; MCM family protein; KEGG: mmp:MMP0030 DNA replication protein; MCM family; putative; Belongs to the MCM family. | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.565 |
ABO34955.1 | pcn | MmarC5_0643 | MmarC5_1695 | MCM family protein; PFAM: magnesium chelatase, ChlI subunit; MCM family protein; KEGG: mmp:MMP0030 DNA replication protein; MCM family; putative; Belongs to the MCM family. | Monomeric archaeal DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.844 |
ABO34955.1 | polB | MmarC5_0643 | MmarC5_1676 | MCM family protein; PFAM: magnesium chelatase, ChlI subunit; MCM family protein; KEGG: mmp:MMP0030 DNA replication protein; MCM family; putative; Belongs to the MCM family. | DNA polymerase II small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.528 |
ABO34955.1 | priS | MmarC5_0643 | MmarC5_1606 | MCM family protein; PFAM: magnesium chelatase, ChlI subunit; MCM family protein; KEGG: mmp:MMP0030 DNA replication protein; MCM family; putative; Belongs to the MCM family. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.834 |
ABO34955.1 | rfcS | MmarC5_0643 | MmarC5_1210 | MCM family protein; PFAM: magnesium chelatase, ChlI subunit; MCM family protein; KEGG: mmp:MMP0030 DNA replication protein; MCM family; putative; Belongs to the MCM family. | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.885 |
ABO35420.1 | ABO34875.1 | MmarC5_1119 | MmarC5_0561 | Replicative DNA helicase Mcm; PFAM: magnesium chelatase, ChlI subunit; MCM family protein; KEGG: mmp:MMP0470 MCM family related protein; Belongs to the MCM family. | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | 0.926 |