STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (126 aa)    
Predicted Functional Partners:
ABO34372.1
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: mmp:MMP1520 ATP/GTP-binding site motif A (P-loop):HypB/UreG, nucleotide-binding:hydrogenase accessory protein HypB.
 
 
 0.992
ABO35672.1
PFAM: Protein of unknown function DUF54; KEGG: mmp:MMP0300 hypothetical protein.
  
    0.979
ABO35180.1
Cobyrinic acid a,c-diamide synthase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
 
 0.921
ABO35699.1
PFAM: cobalamin synthesis protein, P47K; KEGG: mmp:MMP0271 ATP binding putative nickel incorporation protein.
  
 
 0.910
ABO35682.1
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: mmp:MMP0289 hydrogenase expression/formation protein.
 
  
 0.902
ABO34512.1
PFAM: nickel-dependent hydrogenase, large subunit; KEGG: mmp:MMP1382 coenzyme F420-reducing hydrogenase subunit alpha.
 
 
 0.900
ABO34964.1
PFAM: nickel-dependent hydrogenase, large subunit; KEGG: mmp:MMP0823 coenzyme F420-non-reducing hydrogenase subunit alpha; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
 
 0.894
ABO36009.1
PFAM: nickel-dependent hydrogenase, large subunit; KEGG: mmp:MMP1694 F420-non-reducing hydrogenase subunit alpha.
  
 
 0.894
ABO34961.1
PFAM: nickel-dependent hydrogenase, large subunit; KEGG: mmp:MMP0820 coenzyme F420-reducing hydrogenase subunit alpha; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.893
ABO35696.1
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: mmp:MMP0274 hydrogenase expression/formation protein.
 
  
 0.882
Your Current Organism:
Methanococcus maripaludis C5
NCBI taxonomy Id: 402880
Other names: M. maripaludis C5, Methanococcus maripaludis str. C5, Methanococcus maripaludis strain C5
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.