node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABO34657.1 | queC | MmarC5_0341 | MmarC5_1470 | KEGG: mmp:MMP1250 6-pyruvoyl tetrahydropterin synthase. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.988 |
ABO34657.1 | queE | MmarC5_0341 | MmarC5_1600 | KEGG: mmp:MMP1250 6-pyruvoyl tetrahydropterin synthase. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
ABO34657.1 | tgtA | MmarC5_0341 | MmarC5_0996 | KEGG: mmp:MMP1250 6-pyruvoyl tetrahydropterin synthase. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.814 |
ABO34657.1 | tmk | MmarC5_0341 | MmarC5_0559 | KEGG: mmp:MMP1250 6-pyruvoyl tetrahydropterin synthase. | dTMP kinase; PFAM: thymidylate kinase; KEGG: mmp:MMP1034 thymidylate kinase. | 0.696 |
ABO35702.1 | queC | MmarC5_1404 | MmarC5_1470 | PFAM: tRNA pseudouridine synthase; KEGG: mmp:MMP0268 tRNA pseudouridine synthase related. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.739 |
ABO35702.1 | tgtA | MmarC5_1404 | MmarC5_0996 | PFAM: tRNA pseudouridine synthase; KEGG: mmp:MMP0268 tRNA pseudouridine synthase related. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.493 |
ABO35702.1 | tmk | MmarC5_1404 | MmarC5_0559 | PFAM: tRNA pseudouridine synthase; KEGG: mmp:MMP0268 tRNA pseudouridine synthase related. | dTMP kinase; PFAM: thymidylate kinase; KEGG: mmp:MMP1034 thymidylate kinase. | 0.460 |
ABO35702.1 | trm1 | MmarC5_1404 | MmarC5_1472 | PFAM: tRNA pseudouridine synthase; KEGG: mmp:MMP0268 tRNA pseudouridine synthase related. | N(2),N(2)-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.766 |
ABO35768.1 | egsA | MmarC5_1471 | MmarC5_1469 | KEGG: mmp:MMP0227 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | Glycerol-1-phosphate dehydrogenase (NAD(P)(+)); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. | 0.613 |
ABO35768.1 | queC | MmarC5_1471 | MmarC5_1470 | KEGG: mmp:MMP0227 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.769 |
ABO35768.1 | queE | MmarC5_1471 | MmarC5_1600 | KEGG: mmp:MMP0227 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.989 |
ABO35768.1 | trm1 | MmarC5_1471 | MmarC5_1472 | KEGG: mmp:MMP0227 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | N(2),N(2)-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.537 |
crcB | queC | MmarC5_0313 | MmarC5_1470 | Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.765 |
egsA | ABO35768.1 | MmarC5_1469 | MmarC5_1471 | Glycerol-1-phosphate dehydrogenase (NAD(P)(+)); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. | KEGG: mmp:MMP0227 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | 0.613 |
egsA | queC | MmarC5_1469 | MmarC5_1470 | Glycerol-1-phosphate dehydrogenase (NAD(P)(+)); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.806 |
queC | ABO34657.1 | MmarC5_1470 | MmarC5_0341 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | KEGG: mmp:MMP1250 6-pyruvoyl tetrahydropterin synthase. | 0.988 |
queC | ABO35702.1 | MmarC5_1470 | MmarC5_1404 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | PFAM: tRNA pseudouridine synthase; KEGG: mmp:MMP0268 tRNA pseudouridine synthase related. | 0.739 |
queC | ABO35768.1 | MmarC5_1470 | MmarC5_1471 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | KEGG: mmp:MMP0227 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. | 0.769 |
queC | crcB | MmarC5_1470 | MmarC5_0313 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | 0.765 |
queC | egsA | MmarC5_1470 | MmarC5_1469 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Glycerol-1-phosphate dehydrogenase (NAD(P)(+)); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. | 0.806 |