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mptA protein (Methanococcus maripaludis C5) - STRING interaction network
"mptA" - GTP cyclohydrolase MptA in Methanococcus maripaludis C5
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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mptAGTP cyclohydrolase MptA; Converts GTP to 7,8-dihydro-D-neopterin 2’,3’-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin (315 aa)    
Predicted Functional Partners:
ABO35741.1
Cyclic phosphodiesterase MptB; KEGG- mmp-MMP0230 hypothetical protein; TIGRFAM- metal dependent phophohydrolase; PFAM- metal-dependent phosphohydrolase, HD sub domain; SMART- metal-dependent phosphohydrolase, HD region (228 aa)
 
   
  0.965
mptD
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family (124 aa)
 
     
  0.947
ABO35944.1
Transcriptional regulator, ArsR family; PFAM- regulatory protein, ArsR; SMART- AAA ATPase; KEGG- mmp-MMP0033 LysR family member (408 aa)
         
  0.938
arfB
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5’-monophosphate deformylase; Catalyzes the hydrolysis of the formamide of 2-amino-5- formylamino-6-ribosylamino-4(3H)-pyrimidinone 5’-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5’- phosphate (APy) (221 aa)
       
    0.904
moaA
Probable GTP 3’,8-cyclase; Catalyzes the cyclization of GTP to (8S)-3’,8-cyclo-7,8- dihydroguanosine 5’-triphosphate; Belongs to the radical SAM superfamily. MoaA family (298 aa)
         
    0.900
cofG
FO synthase subunit 1; Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (352 aa)
         
  0.838
ABO35940.1
KEGG- mmp-MMP0037 hypothetical protein; TIGRFAM- metal dependent phophohydrolase; PFAM- metal-dependent phosphohydrolase, HD sub domain; SMART- metal-dependent phosphohydrolase, HD region (194 aa)
 
          0.818
mptE
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family (238 aa)
         
  0.811
ABO36100.1
PFAM- pyruvate kinase; KEGG- mmp-MMP1605 pyruvate kinase; Belongs to the pyruvate kinase family (447 aa)
       
    0.808
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family (139 aa)
       
  0.803
Your Current Organism:
Methanococcus maripaludis C5
NCBI taxonomy Id: 402880
Other names: M. maripaludis C5, Methanococcus maripaludis C5, Methanococcus maripaludis str. C5, Methanococcus maripaludis strain C5
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