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hisF protein (Parvibaculum lavamentivorans) - STRING interaction network
"hisF" - Imidazole glycerol phosphate synthase subunit HisF in Parvibaculum lavamentivorans
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (253 aa)    
Predicted Functional Partners:
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (216 aa)
  0.999
hisB
PFAM- imidazoleglycerol-phosphate dehydratase; KEGG- rru-Rru_A3597 imidazoleglycerol-phosphate dehydratase (203 aa)
  0.999
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM- phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM- histidine biosynthesis protein; KEGG- sme-SMc02570 probable phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase protein (243 aa)
 
 
0.998
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (150 aa)
   
  0.998
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (431 aa)
 
  0.995
Plav_0600
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (325 aa)
 
 
  0.978
hisC
TIGRFAM- histidinol-phosphate aminotransferase; PFAM- aminotransferase class V; aminotransferase class I and II; KEGG- bra-BRADO6463 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily (373 aa)
 
 
  0.973
hisE
PFAM- phosphoribosyl-ATP pyrophosphohydrolase; KEGG- swi-Swit_2565 phosphoribosyl-ATP pyrophosphohydrolase (109 aa)
 
   
  0.966
purH
Bifunctional purine biosynthesis protein PurH; TIGRFAM- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG- bms-BR1816 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (537 aa)
   
 
  0.858
Plav_1236
KEGG- rpc-RPC_0305 hypothetical protein (162 aa)
              0.853
Your Current Organism:
Parvibaculum lavamentivorans
NCBI taxonomy Id: 402881
Other names: P. lavamentivorans DS-1, Parvibaculum lavamentivorans, Parvibaculum lavamentivorans DS-1, Parvibaculum lavamentivorans str. DS-1, Parvibaculum lavamentivorans strain DS-1
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