node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Plav_2248 | mtnA | Plav_2248 | Plav_2247 | PFAM: class II aldolase/adducin family protein; KEGG: rru:Rru_A0359 class II aldolase/adducin-like. | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.989 |
Plav_2248 | mtnD | Plav_2248 | Plav_1853 | PFAM: class II aldolase/adducin family protein; KEGG: rru:Rru_A0359 class II aldolase/adducin-like. | Acireductone dioxygenase ARD; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.512 |
Plav_2248 | mtnP | Plav_2248 | Plav_2245 | PFAM: class II aldolase/adducin family protein; KEGG: rru:Rru_A0359 class II aldolase/adducin-like. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.781 |
Plav_2401 | Plav_2402 | Plav_2401 | Plav_2402 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | PFAM: homocysteine S-methyltransferase; KEGG: pae:PA1843 methionine synthase. | 0.962 |
Plav_2401 | mtnA | Plav_2401 | Plav_2247 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.485 |
Plav_2401 | mtnD | Plav_2401 | Plav_1853 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Acireductone dioxygenase ARD; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.489 |
Plav_2402 | Plav_2401 | Plav_2402 | Plav_2401 | PFAM: homocysteine S-methyltransferase; KEGG: pae:PA1843 methionine synthase. | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.962 |
Plav_2402 | mtnA | Plav_2402 | Plav_2247 | PFAM: homocysteine S-methyltransferase; KEGG: pae:PA1843 methionine synthase. | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.599 |
Plav_2402 | mtnD | Plav_2402 | Plav_1853 | PFAM: homocysteine S-methyltransferase; KEGG: pae:PA1843 methionine synthase. | Acireductone dioxygenase ARD; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.519 |
Plav_2609 | mtnA | Plav_2609 | Plav_2247 | PFAM: class II aldolase/adducin family protein; KEGG: pat:Patl_3366 class II aldolase/adducin-like. | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.437 |
Plav_2609 | mtnD | Plav_2609 | Plav_1853 | PFAM: class II aldolase/adducin family protein; KEGG: pat:Patl_3366 class II aldolase/adducin-like. | Acireductone dioxygenase ARD; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.459 |
Plav_2707 | mtnA | Plav_2707 | Plav_2247 | PFAM: class II aldolase/adducin family protein; KEGG: hne:HNE_2063 aldolase, class II. | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.437 |
Plav_2707 | mtnD | Plav_2707 | Plav_1853 | PFAM: class II aldolase/adducin family protein; KEGG: hne:HNE_2063 aldolase, class II. | Acireductone dioxygenase ARD; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.459 |
mtnA | Plav_2248 | Plav_2247 | Plav_2248 | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | PFAM: class II aldolase/adducin family protein; KEGG: rru:Rru_A0359 class II aldolase/adducin-like. | 0.989 |
mtnA | Plav_2401 | Plav_2247 | Plav_2401 | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.485 |
mtnA | Plav_2402 | Plav_2247 | Plav_2402 | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | PFAM: homocysteine S-methyltransferase; KEGG: pae:PA1843 methionine synthase. | 0.599 |
mtnA | Plav_2609 | Plav_2247 | Plav_2609 | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | PFAM: class II aldolase/adducin family protein; KEGG: pat:Patl_3366 class II aldolase/adducin-like. | 0.437 |
mtnA | Plav_2707 | Plav_2247 | Plav_2707 | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | PFAM: class II aldolase/adducin family protein; KEGG: hne:HNE_2063 aldolase, class II. | 0.437 |
mtnA | mtnB | Plav_2247 | Plav_1852 | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Class II aldolase/adducin family protein; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.988 |
mtnA | mtnC | Plav_2247 | Plav_1854 | eIF-2B alpha/beta/delta-related uncharacterized protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.748 |