STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)    
Predicted Functional Partners:
Plav_1435
TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: mmr:Mmar10_2846 succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.996
Plav_1436
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; KEGG: mlo:mll4260 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.976
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.975
Plav_3598
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: sme:SMc01126 NADP-dependent malic enzyme protein.
  
 
 0.973
Plav_1433
TIGRFAM: Succinate dehydrogenase cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: rpe:RPE_0510 succinate dehydrogenase, cytochrome b subunit.
  
 
 0.967
Plav_0593
TIGRFAM: malate synthase A; PFAM: malate synthase; KEGG: malate synthase; Belongs to the malate synthase family.
    
 0.937
Plav_1434
TIGRFAM: Succinate dehydrogenase hydrophobic membrane anchor; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: mlo:mll4265 succinate dehydrogenase cytochrome b small subunit.
  
 
 0.922
Plav_0856
Citrate synthase; PFAM: regulatory protein MerR; Citrate synthase; KEGG: rxy:Rxyl_2556 citrate synthase.
  
 0.894
Plav_0857
PFAM: Citrate synthase; KEGG: atu:Atu5306 citrate synthase; Belongs to the citrate synthase family.
  
 0.894
Plav_3181
TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: bov:BOV_1106 citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 0.894
Your Current Organism:
Parvibaculum lavamentivorans
NCBI taxonomy Id: 402881
Other names: P. lavamentivorans DS-1, Parvibaculum lavamentivorans DS-1, Parvibaculum lavamentivorans str. DS-1, Parvibaculum lavamentivorans strain DS-1
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