STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pmob_0219TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tme:Tmel_1243 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (432 aa)    
Predicted Functional Partners:
purC
KEGG: tte:TTE0588 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase.
 
 0.997
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 0.994
Pmob_1660
Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: tme:Tmel_1545 IMP cyclohydrolase.
  
 0.983
purH
KEGG: ctc:CTC01962 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region.
  
 0.983
Pmob_1960
PFAM: glutamine amidotransferase class-II; KEGG: tte:TTE0812 Glutamine phosphoribosylpyrophosphate amidotransferase.
 
 
 0.962
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 0.955
Pmob_1955
PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: ppe:PEPE_1467 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase.
  
  
 0.945
adk
Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 0.938
purD
KEGG: cpr:CPR_0676 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family.
  
 
 0.934
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.925
Your Current Organism:
Petrotoga mobilis
NCBI taxonomy Id: 403833
Other names: P. mobilis SJ95, Petrotoga mobilis DSM 10674, Petrotoga mobilis SJ95, Petrotoga mobilis str. SJ95, Petrotoga mobilis strain SJ95
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