STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfiDeoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (221 aa)    
Predicted Functional Partners:
Pmob_1171
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
       0.791
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
       0.784
Pmob_1174
PFAM: major facilitator superfamily MFS_1; KEGG: tme:Tmel_0816 major facilitator superfamily MFS_1.
       0.773
Pmob_1175
TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; KEGG: tpt:Tpet_0409 Mg chelatase, subunit ChlI.
       0.675
Pmob_1176
PFAM: nuclease (SNase domain protein); KEGG: tme:Tmel_0612 hypothetical protein.
       0.675
Pmob_1167
KEGG: fno:Fnod_1645 hypothetical protein.
       0.538
Pmob_1168
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: fno:Fnod_1644 pyridoxal-5'-phosphate-dependent protein beta subunit.
       0.538
Pmob_1169
KEGG: fno:Fnod_1643 hypothetical protein.
       0.538
Pmob_1170
PFAM: cobalamin B12-binding domain protein; D-Lysine 56-aminomutase alpha subunit; KEGG: fno:Fnod_1642 cobalamin B12-binding domain protein.
       0.538
Pmob_1177
PFAM: GCN5-related N-acetyltransferase; KEGG: tde:TDE2161 acetyltransferase, GNAT family.
       0.535
Your Current Organism:
Petrotoga mobilis
NCBI taxonomy Id: 403833
Other names: P. mobilis SJ95, Petrotoga mobilis DSM 10674, Petrotoga mobilis SJ95, Petrotoga mobilis str. SJ95, Petrotoga mobilis strain SJ95
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