node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carA | carB | Gbem_1898 | Gbem_1900 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | 0.999 |
carA | pyrB | Gbem_1898 | Gbem_1896 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | Gbem_1898 | Gbem_1897 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.997 |
carA | pyrD | Gbem_1898 | Gbem_2399 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.948 |
carA | pyrE | Gbem_1898 | Gbem_2328 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.922 |
carA | pyrF | Gbem_1898 | Gbem_2890 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.922 |
carA | pyrH | Gbem_1898 | Gbem_2754 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.402 |
carA | pyrR | Gbem_1898 | Gbem_1895 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Pyrimidine operon regulator and uracil phosphoribosyltransferase PyrR; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.903 |
carA | upp | Gbem_1898 | Gbem_0463 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.611 |
carB | carA | Gbem_1900 | Gbem_1898 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
carB | pyrB | Gbem_1900 | Gbem_1896 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carB | pyrC | Gbem_1900 | Gbem_1897 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.995 |
carB | pyrD | Gbem_1900 | Gbem_2399 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.950 |
carB | pyrE | Gbem_1900 | Gbem_2328 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.936 |
carB | pyrF | Gbem_1900 | Gbem_2890 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.940 |
carB | pyrH | Gbem_1900 | Gbem_2754 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.449 |
carB | pyrR | Gbem_1900 | Gbem_1895 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Pyrimidine operon regulator and uracil phosphoribosyltransferase PyrR; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.910 |
carB | upp | Gbem_1900 | Gbem_0463 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.598 |
pyrB | carA | Gbem_1896 | Gbem_1898 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
pyrB | carB | Gbem_1896 | Gbem_1900 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | 0.999 |