node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gbem_0542 | Gbem_2106 | Gbem_0542 | Gbem_2106 | acyl-CoA synthetase, AMP-forming; Belongs to the ATP-dependent AMP-binding enzyme family. | Flavin oxidoreductase, PfaD family, putative. | 0.916 |
Gbem_0542 | hemL | Gbem_0542 | Gbem_3927 | acyl-CoA synthetase, AMP-forming; Belongs to the ATP-dependent AMP-binding enzyme family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.841 |
Gbem_2106 | Gbem_0542 | Gbem_2106 | Gbem_0542 | Flavin oxidoreductase, PfaD family, putative. | acyl-CoA synthetase, AMP-forming; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.916 |
Gbem_2106 | gltA-1 | Gbem_2106 | Gbem_1652 | Flavin oxidoreductase, PfaD family, putative. | Citrate synthase; Belongs to the citrate synthase family. | 0.653 |
Gbem_2106 | hemA | Gbem_2106 | Gbem_0407 | Flavin oxidoreductase, PfaD family, putative. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.441 |
Gbem_2106 | hemB | Gbem_2106 | Gbem_0410 | Flavin oxidoreductase, PfaD family, putative. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.474 |
Gbem_2106 | hemD | Gbem_2106 | Gbem_0409 | Flavin oxidoreductase, PfaD family, putative. | Uroporphyrinogen III C2,C7-methyltransferase and uroporphyrinogen III synthase. | 0.491 |
Gbem_2106 | hemE | Gbem_2106 | Gbem_0016 | Flavin oxidoreductase, PfaD family, putative. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.521 |
Gbem_2106 | hemL | Gbem_2106 | Gbem_3927 | Flavin oxidoreductase, PfaD family, putative. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.561 |
Gbem_2106 | thiE/thiD | Gbem_2106 | Gbem_3462 | Flavin oxidoreductase, PfaD family, putative. | 4-amino-5-hydroxymethyl-2-methylpyrimidine- phosphate kinase and thiamin monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.608 |
cysG | hemA | Gbem_0405 | Gbem_0407 | Precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase, putative. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.849 |
cysG | hemB | Gbem_0405 | Gbem_0410 | Precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase, putative. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.763 |
cysG | hemC | Gbem_0405 | Gbem_0408 | Precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase, putative. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.940 |
cysG | hemD | Gbem_0405 | Gbem_0409 | Precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase, putative. | Uroporphyrinogen III C2,C7-methyltransferase and uroporphyrinogen III synthase. | 0.999 |
cysG | hemL | Gbem_0405 | Gbem_3927 | Precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase, putative. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.854 |
gltA-1 | Gbem_2106 | Gbem_1652 | Gbem_2106 | Citrate synthase; Belongs to the citrate synthase family. | Flavin oxidoreductase, PfaD family, putative. | 0.653 |
gltA-1 | hemL | Gbem_1652 | Gbem_3927 | Citrate synthase; Belongs to the citrate synthase family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.530 |
hemA | Gbem_2106 | Gbem_0407 | Gbem_2106 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Flavin oxidoreductase, PfaD family, putative. | 0.441 |
hemA | cysG | Gbem_0407 | Gbem_0405 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase, putative. | 0.849 |
hemA | hemB | Gbem_0407 | Gbem_0410 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen synthase; Belongs to the ALAD family. | 0.898 |