STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (463 aa)    
Predicted Functional Partners:
BcDW1_7124
Putative dynein heavy chain protein.
    
 0.996
BcDW1_8885
Putative nuclear distribution protein.
    
 
 0.941
BcDW1_7058
Putative gdsl-like protein.
    
 0.939
BcDW1_1547
Putative nuclear movement protein nudc protein.
    
 0.914
BcDW1_6312
Putative cytoplasmic dynein 1 intermediate chain 2 protein.
   
 0.912
BcDW1_11048
Putative platelet-activating factor acetylhydrolase protein.
     
 0.904
BcDW1_6471
Putative phospholipase.
     
 0.904
BcDW1_9409
Putative dynamitin-like protein.
    
 0.894
BcDW1_4368
Putative cap-gly domain-containing protein.
    
 0.876
BcDW1_11035
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
    
 0.863
Your Current Organism:
Botrytis cinerea BcDW1
NCBI taxonomy Id: 1290391
Other names: B. cinerea BcDW1, Botryotinia fuckeliana BcDW1
Server load: medium (42%) [HD]