STRINGSTRING
LIS1 protein (Botrytis cinerea) - STRING interaction network
"LIS1" - Nuclear distribution protein PAC1 in Botrytis cinerea
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIS1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein- mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family (463 aa)    
Predicted Functional Partners:
M7TLA2
annotation not available (4345 aa)
       
 
  0.958
M7UT44
annotation not available (1334 aa)
       
 
  0.915
M7TMA3
annotation not available (875 aa)
       
 
  0.900
M7US60
Patatin-like phospholipase domain-containing protein; Lipid hydrolase (820 aa)
         
    0.900
M7U3W1
annotation not available (776 aa)
         
    0.900
M7TM83
annotation not available (616 aa)
       
 
  0.879
M7TAE5
annotation not available (664 aa)
       
  0.855
M7U139
annotation not available (97 aa)
       
 
  0.838
M7UMH8
annotation not available (548 aa)
       
  0.819
M7TLF0
annotation not available (434 aa)
     
 
  0.816
Your Current Organism:
Botrytis cinerea
NCBI taxonomy Id: 40559
Other names: B. cinerea, Botryotinia fuckeliana, Botrytis cinerea, Botrytis sp. CA25, Botrytis sp. CB17, Sclerotinia fuckeliana
Server load: low (22%) [HD]