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endA protein (Methanococcus vannielii) - STRING interaction network
"endA" - tRNA-splicing endonuclease in Methanococcus vannielii
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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endAtRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5’- and 3’-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’ cyclic phosphate and 5’-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (177 aa)    
Predicted Functional Partners:
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the ATCase/OTCase family (305 aa)
   
     
  0.935
lig
DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (573 aa)
         
  0.919
trpS
Tryptophan--tRNA ligase; TIGRFAM- tryptophanyl-tRNA synthetase; PFAM- aminoacyl-tRNA synthetase class Ib; KEGG- mmp-MMP1592 tryptophanyl-tRNA synthetase (358 aa)
         
  0.881
Mevan_0455
PFAM- Malate/L-lactate dehydrogenase; KEGG- mmp-MMP1133 L-sulfolactate dehydrogenase/(S)-hydroxyglutaric acid dehydrogenase (345 aa)
              0.856
Mevan_1004
PFAM- homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG- mmp-MMP1702 homoserine dehydrogenase (337 aa)
           
  0.842
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3’- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3’-trailer from precursor tRNA; Belongs to the RNase Z family (315 aa)
   
   
  0.775
pheS
TIGRFAM- phenylalanyl-tRNA synthetase, alpha subunit; PFAM- phenylalanyl-tRNA synthetase class IIc; KEGG- mmp-MMP1496 phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily (501 aa)
              0.693
pheT
TIGRFAM- phenylalanyl-tRNA synthetase, beta subunit; PFAM- tRNA synthetase B5; KEGG- mmp-MMP1255 phenylalanyl-tRNA synthetase beta subunit (554 aa)
              0.693
tyrS
Tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily (319 aa)
     
   
  0.688
hisS
Histidine--tRNA ligase; TIGRFAM- histidyl-tRNA synthetase; PFAM- tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; KEGG- mmp-MMP1614 histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family (418 aa)
   
   
  0.687
Your Current Organism:
Methanococcus vannielii
NCBI taxonomy Id: 406327
Other names: M. vannielii SB, Methanococcus vannielii, Methanococcus vannielii SB, Methanococcus vannielii str. SB, Methanococcus vannielii strain SB
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