STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (338 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.994
ABR54460.1
KEGG: mmp:MMP1239 hypothetical protein.
  
    0.972
ABR55119.1
PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: mmp:MMP0484 possible sodium/proton antiporter.
  
  
 0.968
ABR55494.1
PFAM: Exonuclease VII small subunit; KEGG: mmp:MMP0731 exonuclease VII, small subunit related protein.
  
    0.966
ABR55024.1
TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: mmp:MMP0119 biotin--protein ligase.
  
 
 0.938
ABR53969.1
PFAM: aminotransferase class-III; KEGG: mmp:MMP0865 aminotransferase (subgroup II) similar to adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.935
ABR55031.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mmp:MMP0126 biotin synthase.
  
  
 
0.925
ABR54104.1
KEGG: mmp:MMP0361 hypothetical protein.
   
    0.897
ABR54833.1
KEGG: mmp:MMP1620 hypothetical protein.
   
    0.827
ABR55473.1
PFAM: protein of unknown function DUF752; KEGG: mmp:MMP0703 hypothetical protein.
   
    0.813
Your Current Organism:
Methanococcus vannielii
NCBI taxonomy Id: 406327
Other names: M. vannielii SB, Methanococcus vannielii SB, Methanococcus vannielii str. SB, Methanococcus vannielii strain SB
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.