STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ABR55235.1Putative thymidine phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. (505 aa)    
Predicted Functional Partners:
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
 
   
 0.858
ABR54254.1
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: mmp:MMP1016 hypothetical protein.
  
  
 0.826
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
  
 0.795
ABR54413.1
PFAM: peptidylprolyl isomerase FKBP-type; KEGG: mmp:MMP1190 peptidylprolyl isomerase, FKBP-type.
     
 0.776
ABR55340.1
PFAM: peptidylprolyl isomerase FKBP-type; KEGG: mmp:MMP0572 peptidylprolyl isomerase, FKBP-type.
     
 0.773
thyA
Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
     
 0.653
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.634
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
     
 0.628
ABR55236.1
PFAM: Protein of unknown function DUF63; KEGG: mmp:MMP0328 hypothetical protein.
 
     0.627
ABR55131.1
TIGRFAM: phage tail protein I; PFAM: phosphoesterase RecJ domain protein; DHHA2 domain protein; KEGG: mmp:MMP0219 putative manganese-dependent inorganic pyrophosphatase.
     
 0.625
Your Current Organism:
Methanococcus vannielii
NCBI taxonomy Id: 406327
Other names: M. vannielii SB, Methanococcus vannielii SB, Methanococcus vannielii str. SB, Methanococcus vannielii strain SB
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