node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
XNC1_0620 | XNC1_2740 | XNC1_0620 | XNC1_2740 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.690 |
XNC1_0620 | ecfG | XNC1_0620 | XNC1_4087 | Conserved hypothetical protein. | Putative membrane protein. | 0.691 |
XNC1_0620 | lapA | XNC1_0620 | XNC1_2413 | Conserved hypothetical protein. | Inner membrane protein yciS; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.709 |
XNC1_0620 | lptC | XNC1_0620 | XNC1_4193 | Conserved hypothetical protein. | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.716 |
XNC1_0620 | mukE | XNC1_0620 | XNC1_1576 | Conserved hypothetical protein. | Putative killing protein suppressor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. | 0.703 |
XNC1_0620 | mukF | XNC1_0620 | XNC1_1575 | Conserved hypothetical protein. | mukF protein (killing factor KICB); Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. | 0.696 |
XNC1_0620 | proQ | XNC1_0620 | XNC1_1793 | Conserved hypothetical protein. | Putative structural element which influences activation of ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.760 |
XNC1_0620 | rseA | XNC1_0620 | XNC1_3268 | Conserved hypothetical protein. | Anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytop [...] | 0.729 |
XNC1_0620 | seqA | XNC1_0620 | XNC1_1386 | Conserved hypothetical protein. | Negative modulator of replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.692 |
XNC1_0620 | syd | XNC1_0620 | XNC1_4017 | Conserved hypothetical protein. | Interacts with secY; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.738 |
XNC1_2740 | XNC1_0620 | XNC1_2740 | XNC1_0620 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.690 |
XNC1_2740 | ecfG | XNC1_2740 | XNC1_4087 | Conserved hypothetical protein. | Putative membrane protein. | 0.439 |
XNC1_2740 | lapA | XNC1_2740 | XNC1_2413 | Conserved hypothetical protein. | Inner membrane protein yciS; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.493 |
XNC1_2740 | lptC | XNC1_2740 | XNC1_4193 | Conserved hypothetical protein. | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.597 |
XNC1_2740 | proQ | XNC1_2740 | XNC1_1793 | Conserved hypothetical protein. | Putative structural element which influences activation of ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.676 |
XNC1_2740 | rseA | XNC1_2740 | XNC1_3268 | Conserved hypothetical protein. | Anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytop [...] | 0.706 |
XNC1_2740 | seqA | XNC1_2740 | XNC1_1386 | Conserved hypothetical protein. | Negative modulator of replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.575 |
XNC1_2740 | syd | XNC1_2740 | XNC1_4017 | Conserved hypothetical protein. | Interacts with secY; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.462 |
ecfG | XNC1_0620 | XNC1_4087 | XNC1_0620 | Putative membrane protein. | Conserved hypothetical protein. | 0.691 |
ecfG | XNC1_2740 | XNC1_4087 | XNC1_2740 | Putative membrane protein. | Conserved hypothetical protein. | 0.439 |