STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (878 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
   
 
 0.935
pck
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
     
 0.934
mdh
Malate dehydrogenase, NAD(P)-binding; Catalyzes the reversible oxidation of malate to oxaloacetate.
     
 0.934
pps
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.934
pykA
Pyruvate kinase II, glucose-stimulated; Belongs to the pyruvate kinase family.
     
 0.913
pykF
Pyruvate kinase I (formerly F), fructose-stimulated.
     
 0.913
aceB
Malate synthase A.
     
 0.868
gltB
Glutamate synthase, large subunit.
 
  
 0.861
gltA
Citrate synthase; Belongs to the citrate synthase family.
     
 0.827
purU
Formyltetrahydrofolate hydrolase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
     
  0.800
Your Current Organism:
Xenorhabdus bovienii
NCBI taxonomy Id: 406818
Other names: X. bovienii SS-2004, Xenorhabdus bovienii SS-2004, Xenorhabdus bovienii str. SS-2004, Xenorhabdus bovienii strain SS-2004
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