Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
rRNA adenine N(6)-methyltransferase; Ribosomal RNA adenine dimethylase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family (354 aa)
Predicted Functional Partners:
NOL1/NOP2/sun family protein / antitermination NusB domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family (564 aa)
Uncharacterized protein; FUNCTIONS IN- molecular_function unknown; INVOLVED IN- ribosome biogenesis; LOCATED IN- nucleus; EXPRESSED IN- 22 plant structures; EXPRESSED DURING- 13 growth stages; CONTAINS InterPro DOMAIN/s- AARP2CN (InterPro-IPR012948), Protein of unknown func /.../UF663 (InterPro-IPR007034); BEST Arabidopsis thaliana protein match is- P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR-AT1G06720.1); Has 2741 Blast hits to 2088 proteins in 291 species- Archae - 2; Bacteria - 131; Metazoa - 833; Fungi - 650; Plants - 171; Viruses - 49; Other Euka [...] (791 aa)
annotation not available (706 aa)
NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family (611 aa)
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family protein (155 aa)
annotation not available (145 aa)
annotation not available (219 aa)
annotation not available (314 aa)
Protein serine/threonine kinases;ATP binding;catalytics (457 aa)