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TOP3A protein (Solanum lycopersicum) - STRING interaction network
"TOP3A" - DNA topoisomerase 3-alpha in Solanum lycopersicum
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
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TOP3ADNA topoisomerase 3-alpha; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (212 aa)    
Predicted Functional Partners:
Solyc12g006710.1.1
Uncharacterized protein (411 aa)
     
  0.958
Solyc07g042010.2.1
Uncharacterized protein (685 aa)
   
  0.921
Solyc01g103960.2.1
Uncharacterized protein (1180 aa)
   
  0.914
Solyc09g018710.2.1
Uncharacterized protein (410 aa)
   
  0.912
Solyc09g018690.2.1
Uncharacterized protein (507 aa)
   
  0.912
Solyc08g074610.1.1
Uncharacterized protein (550 aa)
   
  0.912
Solyc05g014690.1.1
Uncharacterized protein (1002 aa)
   
  0.912
Solyc02g088430.1.1
Uncharacterized protein (541 aa)
   
  0.912
Solyc01g100280.2.1
Uncharacterized protein (704 aa)
   
  0.912
Solyc01g099500.1.1
Uncharacterized protein (250 aa)
   
  0.912
Your Current Organism:
Solanum lycopersicum
NCBI taxonomy Id: 4081
Other names: Lycopersicon, Lycopersicon (Mill.) Seithe, Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, Lycopersicon lycopersicum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum, Solanum lycopersicum L., tomato
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