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STRINGSTRING
Formin-I2I protein (Solanum lycopersicum) - STRING interaction network
"Formin-I2I" - Formin-like protein in Solanum lycopersicum
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Formin-I2IFormin-like protein; Formin ; Belongs to the formin-like family (955 aa)    
Predicted Functional Partners:
Pro1
Profilin-1; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity) (133 aa)
       
 
  0.912
Solyc12g008590.1.1
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (98 aa)
       
 
  0.886
101254907
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (131 aa)
       
 
  0.886
LOC543830
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (131 aa)
       
 
  0.886
profilin
Profilin-2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity) (131 aa)
       
 
  0.884
101263559
Actin related protein 2; Belongs to the actin family (389 aa)
     
 
  0.865
Tom52
Actin-52; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth (377 aa)
       
 
  0.805
Actin-105
Actin-105; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth (377 aa)
       
 
  0.805
actin
Actin-41; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth (377 aa)
       
 
  0.805
101264601
Uncharacterized protein; Actin ; Belongs to the actin family (377 aa)
       
 
  0.805
Your Current Organism:
Solanum lycopersicum
NCBI taxonomy Id: 4081
Other names: Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum, Solanum lycopersicum L., tomato
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