STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCED19-cis-epoxycarotenoid dioxygenase NCED1, chloroplastic; Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid (ABA) biosynthesis from carotenoids. Required for ABA accumulation upon drought. Required for ABA-mediated regulation of anther/pollen development, including metabolism, cell wall modification and transcription level. Positive regulator of fruit ripening involved in the biosynthesis of abscisic acid (ABA); initiates ABA biosynthesis at the onset of fruit ripening. Modulates the degree of pigmentation and carotenoid composition a [...] (605 aa)    
Predicted Functional Partners:
NSY
Neoxanthin synthase, chloroplastic; Involved in the synthesis of neoxanthin, the last product of carotenoid synthesis and a precursor of abscisic acid. Involved in the beta-carotene biosynthesis ; Belongs to the lycopene cyclase family.
     
 0.977
A0A3Q7G427
Uncharacterized protein.
     
 0.928
A0A3Q7G430
Uncharacterized protein.
     
 0.917
ZEP
Zeaxanthin epoxidase, chloroplastic; Converts zeaxanthin into antheraxanthin and subsequently violaxanthin. Involved in the epoxidation of zeaxanthin. Plays an important role in resistance to stresses, seed development and dormancy.
   
  
 0.740
TAO2
Uncharacterized protein.
      
 0.722
TAO3
Uncharacterized protein.
      
 0.722
A0A3Q7EAA7
Uncharacterized protein.
      
 0.717
CYP707A2
Abscisic acid 8'-hydroxylase CYP707A2; Negative regulator of fruit ripening involved in the oxidative degradation of abscisic acid (ABA).
      
 0.717
CYP707A1
Abscisic acid 8'-hydroxylase CYP707A1; Involved in the oxidative degradation of abscisic acid, especially in pollinated ovaries; Belongs to the cytochrome P450 family.
      
 0.716
LCY1
Lycopene beta cyclase, chloroplastic; Catalyzes the double cyclization reaction which converts lycopene to beta-carotene and neurosporene to beta-zeacarotene.
   
  
 0.716
Your Current Organism:
Solanum lycopersicum
NCBI taxonomy Id: 4081
Other names: Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum L., Solanum lycopersicum var. humboldtii, tomato
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